2021
DOI: 10.1101/2021.11.03.467052
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Nicotinic modulation insecticides act on diverse receptor subtypes with distinct subunit compositions

Abstract: Insect nicotinic acetylcholine receptors (nAChRs) are ligand gated ion channels mainly expressed in the central nervous system of insects. They are the directed targets of nicotinic modulation insecticides including neonicotinoids, the most widely used insecticides in the world. However, the resistance development from pests and the negative impacts on the pollinators affect their applications and create demand for the alternatives. Thus, it is very important to understand the mode of action of these insectici… Show more

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