2015
DOI: 10.2399/ana.15.018
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Nigella sativa protects against formaldehyde-induced neurotoxicity in the rat frontal cortex

Abstract: Formaldehyde (FA) is a compound commonly used in industry and medicine that can react with different macromolecules such as proteins, nucleic acids and low molecular weight substances as amino acids. [1,2] In particular, anatomists and medical students are exposed to FA gas during cadaver dissections. [3,4] Humans are exposed to FA from direct environmental sources like paint, plywood, cosmetics, cigarette smoke, photochemical smog and even various fruits as well as from the metabolism of xenobiotics. [5,6] FA… Show more

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Cited by 2 publications
(1 citation statement)
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“…On the other hand, and opposite to our results, the study of Mohamad [67] showed significant decrease in the levels of NO in the brain tissue of FA-treated rats, due to the effect of superoxide which reduces NO bioavailability by binding to the gaseous molecule and forming the free radical, peroxynitrite.…”
Section: Experimental Studycontrasting
confidence: 55%
“…On the other hand, and opposite to our results, the study of Mohamad [67] showed significant decrease in the levels of NO in the brain tissue of FA-treated rats, due to the effect of superoxide which reduces NO bioavailability by binding to the gaseous molecule and forming the free radical, peroxynitrite.…”
Section: Experimental Studycontrasting
confidence: 55%