Night Blindness, Yellow Vision, and Yellow Skin: Symptoms and Signs of Malabsorption

Pitchon, Elie M.; Sahli, O.; Borruat, François‐Xavier

doi:10.1055/s-2006-926830

Cited by 3 publications

(4 citation statements)

References 4 publications

(7 reference statements)

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“…Vitamin A deficiency can lead to a well-known array of ocular complications, including nyctalopia, xerosis with Bitot spots, and xanthopsia [9, [21][22][23]. If detected early, oral or intramuscular vitamin A replacement can reverse ocular complications prior to permanent vision loss [16,24,25].…”

Section: Introductionmentioning

confidence: 99%

Outer retina changes on optical coherence tomography in vitamin A deficiency

Berkenstock¹,

Castoro²,

Carey³

2020

Int J Retin Vitr

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Background: Vitamin A deficiency is rare in the United States and can be missed in patients with malabsorption syndromes without a high dose of suspicion. Ocular complications of hypovitaminosis A include xerosis and nyctalopia, and to a lesser extent reduction in visual acuity and color vision. Outer retinal changes, as seen on spectral domain optic coherence tomography (SD-OCT), in patients with vitamin A deficiency have previously not been documented. Case presentation: We present two cases with symptoms of severe nyctalopia who were subsequently diagnosed with severe Vitamin A deficiency and their unique findings on SD-OCT of outer nuclear layer diffuse thinning with irregular appearance of the interdigitating zone and the ellipsoid zone as well as normalization after vitamin A supplementation. Conclusions: Outer nuclear layer thinning and disruption of the outer retinal bands on SD-OCT are reversible with correction of vitamin A deficiency. Improvement in visual acuity, color vision, and nyctalopia are possible with early diagnosis and appropriate treatment.

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Section: Introductionmentioning

confidence: 99%

Outer retina changes on optical coherence tomography in vitamin A deficiency

Berkenstock¹,

Castoro²,

Carey³

2020

Int J Retin Vitr

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“…However, oral supplementation in patients with malabsorption may not be effective [7,9]. Without widely accepted guidelines, we empirically treated our patient with a similar regimen as previously published [5]. A total IM dose of 800 000 IU (4 injections over 10 days) resulted in rapid resolution of visual symptoms and normalization of serum vitamin A levels.…”

Section: Markedly Delayed Night Blindness Due To Vitamin a Insufficiency Secondary To Bowel Resectionmentioning

confidence: 95%

“…Night blindness is usually the first symptom to appear and may be accompanied by xanthopsia or blurry vision [3]. In most cases, vitamin A supplementation results in rapid improvement of visual symptoms [4,5].…”

Section: Introductionmentioning

confidence: 99%

Markedly Delayed Night Blindness Due to Vitamin A Insufficiency Secondary to Bowel Resection

Chatzistergiou¹,

Ambresin

Borruat

2021

Klin Monbl Augenheilkd

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“…Therefore, historical evidence regarding dietary deficiencies and basic hematologic and biochemical workup are reasonable. 5 As highlighted by the authors, accurate diagnosis and subsequent appropriate treatment for any patient with bilateral visual field defects atypical for glaucoma require thorough evaluation including appropriate investigations and imaging. In Response: We appreciate the comments by Francis et al regarding our paper ''atypical retinitis pigmentosa masquerading as primary open angle glaucoma.''…”

Section: To the Editormentioning

confidence: 99%