Ninety-one cases of ameloblastoma in an Indian population: A comprehensive review

Abstract

Aim:To assess the cases of ameloblastoma retrospectively for various parameters.Materials and Methods:Ninety-one previously reported cases of ameloblastoma from Government Dental College and Hospitals, Nagpur, were included in this study. Data were collected considering parameters such as age, sex, symptoms, radiographic, histopathology, treatment modalities, and recurrence. Our findings were also compared with world literature.Results:The average age was 32.5 years. Mostly men complained of an asymptomatic swelling and duration of less than one year. Posterior segment and vertical ramus of mandible was the frequently involved site. Radiographically, multilocular appearance was noted more than 60% of the cases. Plexiform and unicystic ameloblastoma occurred frequently. Surgery was the treatment of choice in this review. Recurrence was noted in more than 10% of the cases.Conclusion:There are variations in our review in comparison to reported literature.

Ameloblastomas: Clinicopathological features from 70 cases diagnosed in a single Oral Pathology service in an 8-year period

“…They usually affect younger patients, with mean ages in the third decade of life, with predilection for the posterior mandible ( 17 ). The results of the present study showed that, contrarily to the literature ( 5 , 6 , 9 , 10 , 12 , 13 ) and similarly Hertog et al . ( 11 ), there was no statistically significant difference in the mean age of patients affected by solid and unicystic ameloblastomas; however, the few unicystic ameloblastomas included in the sample precludes any definite conclusion.…”

“…Ameloblastomas can produce extensive bone destruction but are mostly characterized by well-defined radiolucencies surrounded by cortical bone sclerosis, as demonstrated by the present results. Most studies reinforce the idea that ameloblastomas are mainly characterized by multilocular radiolucencies, especially the solid subtype ( 6 , 7 , 12 , 13 ), but some have demonstrated an equal distribution or even predominance of unilocular radiolucencies ( 3 , 5 , 10 ). In the present study, mean greatest diameter of the tumors was 46 mm and, due to large size of some tumors, symptoms such as pain and discharge were found in one third of the cases, similarly to other studies ( 5 - 7 , 13 ).…”

“…Ameloblastomas represent from 0.5% to 1.3% of all diagnosis ( 5 , 9 , 10 , 13 ) and from 22% to 46% (this higher value when excluding keratocystic odontogenic tumors) of all OT diagnosed in Oral Pathology laboratories ( 5 , 12 , 13 ). Apart from being classified as benign entities, these tumors can present local infiltrative growth and are able to produce extensive bone destruction and infiltration to the surrounding soft tissues.…”

Squamous Odontogenic Tumor: Literature Review Focusing on the Radiographic Features and Differential Diagnosis

“…Ameloblastoma is a benign epithelial odontogenic tumor with two quite different intraosseous biologic variants [ 52 ]. The multicystic ameloblastoma (MA) is the most frequent type presenting aggressive and destructive characteristics with the involvement of posterior areas of jaws and impacted third molars in some cases [ 53 ]. Radiographically, MA shows as a radiolucent multilocular lesion with a ‘‘soap-bubbles” aspect associated with expansion and disruption of bone cortical [ 52 , 53 ].…”

“…The multicystic ameloblastoma (MA) is the most frequent type presenting aggressive and destructive characteristics with the involvement of posterior areas of jaws and impacted third molars in some cases [ 53 ]. Radiographically, MA shows as a radiolucent multilocular lesion with a ‘‘soap-bubbles” aspect associated with expansion and disruption of bone cortical [ 52 , 53 ]. A unicistic ameloblastoma (UA) is less aggressive and commonly mimics odontogenic cysts frequently related with teeth in the area, especially, mandible third molars.…”