Ninhydrin Test—an Objective Method for Testing Local Anaesthetic Drugs

Dhunèr, K. G.; Edshage, S; Wilhelm, A

doi:10.1111/j.1399-6576.1960.tb00074.x

Cited by 24 publications

(6 citation statements)

References 10 publications

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“…Skin electrical resistance also increases following traumatic damage to, and local anaesthetic block of, peripheral nerves [3] and, under these circumstances, geographically identical areas of analgesia and increased skin electrical resistance are demonstrated. The correlation between loss of sensation and loss of sweating, associated with changes in skin electrical resistance, has been confirmed for a variety of nerve injuries [4,5] using various techniques [4][5][6][7][8][9].…”

Section: Discussionmentioning

confidence: 99%

Predicting Successful Brachial Plexus Block Using Changes in Skin Electrical Resistance

G¹,

Wilson²,

Curry³

et al. 1988

British Journal of Anaesthesia

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Skin electrical resistance is determined by the degree of sweating of the skin which is, in turn, related to sympathetic nervous system activity in the area concerned. It is increased when the nerves supplying the area are damaged or blocked by local anaesthetic agents. We have assessed the temporal and spatial relationship between the onset of sympathetic and sensory loss in the hand following brachial plexus block in 44 patients. Skin electrical resistance, measured using a simple ohm meter, has been shown to increase within 2 min of brachial plexus blockade with 1% lignocaine and adrenaline 1:200,000. This increase is an early and reliable indicator of subsequent, and occasionally delayed, sensory loss.

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Section: Discussionmentioning

confidence: 99%

Predicting Successful Brachial Plexus Block Using Changes in Skin Electrical Resistance

G¹,

Wilson²,

Curry³

et al. 1988

British Journal of Anaesthesia

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“…No cases have been published in his work. Dhuner et al (1960) reported no neurogenous injury demonstrable by conventional neurological methods or by the ninhydrin method after 41 intraneural blocks. Also Highet (1942) believed intraneural injection of a local anesthetic to be safe.…”

Section: Technique For Avoiding Nerve Injury In Induction Of Nerve Blockmentioning

confidence: 95%

“…Intraneural versus extraneural block Highet (1942) induced the block intraneurally. Other authors who used this technique are Chase, Brandom, Macomber and Wang (1959), Dhuner, Edshage and Wilhelm (1960), Albert and Lofstrom (1961) and Moore (1961). According to Moore, nerve blocking is a measure to obtain "reversible chemical section of the nerve".…”

Section: Previous Investigationsmentioning

confidence: 99%

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Studies on the Hand in Ulnar Nerve Paralysis: A Clinical-Experimental Investigation in Normal and Anomalous Innervation

Mannerfelt

1966

Acta Orthopaedica Scandinavica

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Chapter I. Normal and anomalous pattern of innervation of the ulnar nerve 19 Zone I 19, Normal pattern of innervation 20 Anomalous pattern of innervation 21 Zone II 21 Normal pattern of innervation 23 Anomalous pattern of innervation 25 Zone III 25 Normal pattern of innervation 26 Anomalous pattern of innervation 26 Zone IV 26 Normal pattern of innervation 27 Anomalous pattern of innervation 29 Summary 30 Chapter II. Authors dissection of the ulnar nerve 34 Summary 35 Chapter III. On muscles and tendons of the thumb, index finger and little finger 35 Intrinsic muscles of the thumb 37 Extrinsic muscles of the thumb 40 Intrinsic muscles of the index finger 40 Extrinsic muscles of the index finger 42 Intrinsic muscles of the little finger 43 Extrinsic muscles of the little finger 43 Summary 44 Chapter IV. Author's dissection of muscles, tendons, joints and ligaments around the thumb 44 Attachment of adductor muscles on the first ray 48 Dissection of extensor pollicis longus, extensor pollicis brevis, abductor pollicis brevis and flexor pollicis longus 5 I Adduction experiments on fresh post mortem specimens Summary 55 PART III. ON SOME NORMAL FUNCTIONS OF THE HAND Chapter V 57 Introduction 57 Short survey of some functions of the 3 main nerves of the hand 58 Methods for quantitative evaluation of the sensibility of the hand Considerations on quantitative measurements of the strength of hand muscles 58 Survey of ergometers, ergograhs and more complicated instruments for measuring the strength of the hand 59 Survey of dynamometers suitable for clinical use Summary 61 Chapter VI. Quantitative methods for evaluating strength of muscles supplied by ulnar nerve Previous methods Description of the author's dynamometer Summary 69 Chapter VII. Control series Composition Order of tests performed Methods and standard positions Results Error of the method Standard deviation 78 Results of studies on controls Analysis of normal palmar adduction of the thumb

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“…Reflex sweat secretion may be tested by means of radiant body heating to an increase in body core temperature of 1°C. Local sweat secretion is detected by application of ninhydrine or iodine starch and subsequent registration of colour change of the indicator (55).…”

Section: Tests Of Local Sympathetic Functionmentioning

confidence: 99%

Autonomic neuropathy: the diagnosis

Hilsted

1983

Acta Neurologica Scandinavica

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The diagnosis of autonomic neuropathy is often difficult to establish, since clinical symptoms generally appear late in the course of the disease, and may be non-specific. A number of recently developed quantifiable and reproducible autonomic nerve function tests are reviewed, with emphasis on the physiological basis of the tests and on practical applicability. Finally, diagnostic criteria, based on autonomic nerve function tests, are suggested.

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Ninhydrin Test—an Objective Method for Testing Local Anaesthetic Drugs

Cited by 24 publications

References 10 publications

Predicting Successful Brachial Plexus Block Using Changes in Skin Electrical Resistance

Predicting Successful Brachial Plexus Block Using Changes in Skin Electrical Resistance

Studies on the Hand in Ulnar Nerve Paralysis: A Clinical-Experimental Investigation in Normal and Anomalous Innervation

Autonomic neuropathy: the diagnosis

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