Nipple adenoma arising from axillary accessory breast: a case report

Abstract

Nipple adenoma is a relatively rare benign breast neoplasm, and cases of the disease arising from the axillary accessory breast have very seldom been reported in the English literature. We report a case of nipple adenoma arising from axillary accessory breast including clinical and pathological findings. An 82-year-old woman presented with the complaint of a small painful mass in the right axilla. Physical examination confirmed a well-defined eczematous crusted mass that was 8 mm in size. The diagnosis of nipple adenoma was made from an excisional specimen on the basis of characteristic histological findings. Microscopic structural features included a compact proliferation of small tubules lined by epithelial and myoepithelial cells, and the merging of glandular epithelial cells of the adenoma into squamous epithelial cells in the superficial epidermal layer. Because clinically nipple adenoma may resemble Paget’s disease and pathologically can be misinterpreted as tubular carcinoma, the correct identification of nipple adenoma is an important factor in the differential diagnosis for axillary tumor neoplasms.Virtual slidesThe virtual slide(s) for this article can be found here: http://www.diagnosticpathology.diagnomx.eu/vs/1186821489769063

Nipple adenoma in a female patient presenting with persistent erythema of the right nipple skin: case report, review of the literature, clinical implications, and relevancy to health care providers who evaluate and treat patients with dermatologic conditions of the breast skin

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Surgical management of erosive adenomatosis of the nipple: A case report

“…Our patient was 45; and, to the best of our knowledge, this is one of the very few cases described in black women from sub-Saharan Africa. Localization on supernumerary breast is possible, although exceptional [7] .…”

“…The differential diagnosis mainly arises in the clinic with Paget's disease of the nipple, which is a malignant and unfortunately more common disease [3] . Pathologically, EAN can be mistaken for a tubular carcinoma [7] . Other differential diagnoses such as contact dermatitis, psoriasis and galactophoric ectasia should also be ruled out at initial evaluation [8] .…”

Nipple adenoma, a rare benign tumor in accessory breasts: A case report

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