Nipple-areolar complex: commonest site of breast leiomyoma

Abstract

Breast leiomyomas are extremely rare and commonly seen in the nipple-areolar complex due to the presence of smooth muscle. Identification of this rare benign tumour is based on its location and the presence of spindle cells on histology. We report a case of a breast leiomyoma in a female patient who had a six-year history of a unilateral breast mass. Breast ultrasound and mammography demonstrated a sub-areola mass and an ultrasound-guided core biopsy revealed a benign spindle cell neoplasm with smooth muscle differentiation. The lesion was excised and final histology confirmed a leiomyoma with clear margins.

Mesenchymal Tumors of the Breast: Fibroblastic/Myofibroblastic Lesions and Other Lesions

“…The natural history of leiomyomas in the breast is not well studied. Similar to extramammary locations, they are considered indolent and non-aggressive [73]. The majority of described cases have been excised, aiming for negative margins, with no recorded recurrences or malignant transformations [63,68,70].…”

“…The majority of described cases have been excised, aiming for negative margins, with no recorded recurrences or malignant transformations [63,68,70]. Some believe enucleation is adequate [73]. It has been proposed that typical lesions in the NAC could be observed unless they are symptomatic, cause cosmetic problems [28], or have diagnostic dilemmas.…”

Ultrasound-guided microwave ablation for giant breast leiomyoma: A case report

“…Breast leiomyoma is considered as the rarest non-epithelial tumor of the breast, accounting for less than 1% of all breast neoplasms (1,2), and it usually occurs in middle-aged women. At present, the clinical manifestations, imaging features and differential diagnosis of breast leiomyoma have been reported in the related studies (3)(4)(5), but the treatment of breast leiomyoma is rare. In clinical practice, traditional surgical resection is often chosen for the treatment of large breast leiomyomas.…”