Nipple Lesions of the Breast

Brogi, Edi; Scatena, Cristian

doi:10.1097/pap.0000000000000413

Cited by 3 publications

(1 citation statement)

References 125 publications

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“…Phyllodes tumour was distinguished from fibroadenoma using Rosen's criteria [9] i.e, expansion and increased cellularity of the stromal component with often a leaf like stromal growth pattern. In phyllodes areas of fibroadenomas, stromal mitoses were counted per 10 high power fields (HPF; 400x magnification, -1.6mm²).…”

Section: Resultsmentioning

confidence: 99%

Study of Histopathological Changes in Fibroadenoma of the Breast

Yevoor

2023

Ann of Pathol and Lab Med

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Background: Fibroadenoma of the breast is a relatively frequently occurring tumor. Although often considered a benign tumour, several reports describe a higher risk of subsequent breast carcinoma in patients diagnosed with fibroadenoma. Increased risk depends on presence of complex changes within fibroadenoma, presence of hyperplasia and positive family history for breast cancer. Aims and Objectives: Our main aim was to study the histological variations within the fibroadenoma of the breast and also to identify those lesions with the possible risk of malignancy. Methods: Descriptive study of three years. A total of 250 cases of fibroadenoma were studied. Slides were stained with Hematoxylin and Eosin (H & E) and were thoroughly reviewed. Slides were screened for proliferative epithelial changes, fibrocystic epithelial changes, stromal changes and various other changes such as foci of tubular adenoma and phyllodes tumour. Slides with invasive malignancies were excluded from the study. Result: Apocrine change among fibrocystic changes was the commonest variation within the fibroadenoma. Complex fibroadenoma, moderate and atypical ductal hyperplasia was seen in older age groups. Conclusion: Increased risk of breast cancer is seen patients with presence of hyperplasia and complex fibroadenoma of the breast. So exclusive study of histopathological changes in epithelial and stromal elements of fibroadenoma is required and are essential to be reported so as to alert the clinician for follow up of the patient. This will help in timely management to reduce morbidity and mortality.

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Section: Resultsmentioning

confidence: 99%

Study of Histopathological Changes in Fibroadenoma of the Breast

Yevoor

2023

Ann of Pathol and Lab Med

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Intelligent Ultrasound Imaging for Enhanced Breast Cancer Diagnosis: Ensemble Transfer Learning Strategies

Rao,

Terlapu,

Jayaram

et al. 2024

IEEE Access

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According to WHO statistics for 2018, there are 1.2 million cases and 700,000 deaths from breast cancer (BC) each year, making it the second-highest cause of mortality for women globally. In recent years, advances in artificial (AI) intelligence and machine (ML) learning have shown incredible potential in increasing the accuracy and efficiency of BC diagnosis. This research describes an intelligent BC image analysis system that leverages the capabilities of transfer learning (TLs) with ensemble stacking ML models. As part of this research, we created a model for analyzing ultrasound BC images using cutting-edge TL models such as Inception V3, VGG-19, and VGG-16. We have implemented stacking of ensemble ML models, including MLP (Multi-Layer Perceptron) with different architectures (10 10, 20 20, and 30 30) and Support Vector Machines (SVM) with RBF and Polynomial kernels. We analyzed the effectiveness of the proposed system in performance parameters (accuracy (CA), sensitivity, specificity, and AUC). Compared to the results with existing BC diagnostic systems, the proposed method (Inception V3 + Staking) is superior, with performance parameters 0.947 of AUC and 0.858 of CA values. The proposed BCUI analysis system consists of data collection, pre-processing, transfer learning, ensemble stacking of ML models, and performance evaluation, with comparative analysis demonstrating its superiority over existing methods.

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Adenoma of the Nipple: A Case Report

Beaudoin,

Karmach,

Koehler De Celaya

et al. 2024

Cureus

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Nipple adenomas are rare, benign breast lesions that present similarly to breast malignancies, often manifesting with unilateral bloody discharge, a palpable mass, and/or nipple distortion. Imaging techniques have limited specificity in distinguishing nipple adenomas from malignancy; therefore, clinicians must rely on histologic and immunohistochemistry evaluation. Here, we highlight the case of a 69-year-old woman with bilateral nipple adenomas presenting as an enlarging nipple mass with chronic nipple discharge. Complete lesion resection with clear margins stands as the primary route of management and complete avoidance of re-occurrence. However, partial excision with nipple preservation has been reported to be successful in selected cases.

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Nipple Lesions of the Breast

Cited by 3 publications

References 125 publications

Study of Histopathological Changes in Fibroadenoma of the Breast

Study of Histopathological Changes in Fibroadenoma of the Breast

Intelligent Ultrasound Imaging for Enhanced Breast Cancer Diagnosis: Ensemble Transfer Learning Strategies

Adenoma of the Nipple: A Case Report

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