Nipple reconstruction in autologous breast reconstruction after areola-sparing mastectomy

Opsomer, Dries; Vyncke, Tom; Depypere, Bernard; Stillaert, Filip; Landuyt, Koenraad Van; Blondeel, Phillip

doi:10.1016/j.bjps.2020.10.082

Cited by 7 publications

(11 citation statements)

References 12 publications

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“…Most studies did not show significant differences in overall complication rates; however, wound-related complications and NAC necrosis were more prevalent in NSM patients. 22,24,27,32 A previously published systematic review that mainly focused on oncologic outcomes after NSM and SSM did not find any differences in local recurrence rates at 5 years or disease-free survival. 4 Although aesthetic outcomes, PROs, and quality of life were evaluated as well, no scientific conclusions could be drawn because of the lack of standardized assessment tools.…”

Section: Discussionmentioning

confidence: 84%

“…The study-specific characteristics are summarized in Table 1. 5,6,17,[22][23][24][25][26][27][28][29][30][31]…”

Section: Search Resultsmentioning

confidence: 99%

“…Four studies included both breast cancer patients and patients with a BRCA mutation opting for prophylactic mastectomy. 22,[24][25][26] Seven studies included both unilateral and bilateral mastectomies, 5,22,[24][25][26][27][28] one study only unilateral, 29 and two studies only bilateral (prophylactic) mastectomies. 17,30 Three studies did not specify this, resulting in at least 1436 unilateral and 2170 bilateral mastectomies.…”

Section: Study Characteristicsmentioning

confidence: 99%

“…Nipple reconstruction after SSM was reported in seven studies, of which four studies specified the type of nipple reconstruction after SSM (eg, intradermal tattooing, local transposition flaps). 6,22,24,26,27,29,30 Quality Assessment Six studies were rated as good, eight studies were rated as fair, and one study was rated as poor. Adjustment for potential confounding was not consistent across studies; seven studies adjusted for age, four adjusted for prognostic factors such as tumor grade and treatment, whereas other studies adjusted for income or insurance status (Table 2).…”

Section: Study Characteristicsmentioning

confidence: 99%

“…ContinuedPlastic and Reconstructive Surgery • July 2023 18e and two studies, only autologous breast reconstructions 27,31. Sample sizes ranged from 44 to 1866 patients, with a mean of 73 patients undergoing NSM and 227 patients undergoing SSM.…”

mentioning

confidence: 99%

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Quality of life, patient satisfaction, and complications after nipple-sparing versus skin-sparing mastectomy followed by immediate breast reconstruction. A systematic review and meta-analysis.

Clarijs

Peeters

Dongen

et al. 2023

Plastic &Amp; Reconstructive Surgery

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Background: Nipple-sparing mastectomy (NSM) has emerged as an alternative procedure for skin-sparing mastectomy (SSM), followed by immediate breast reconstruction. Because oncologic safety appears similar, patient-reported outcomes (PROs) and complication risks may guide decision-making in individual patients. Therefore, the aim of this systematic review was to compare PROs and complication rates after NSM and SSM. Methods: A systematic literature review evaluating NSM versus SSM was performed using the Embase, MEDLINE, and Cochrane databases. Methodologic quality of the included studies was assessed using the Newcastle-Ottawa Quality Assessment Form for Cohort Studies. Primary outcomes were PROs and complications. Studies that evaluated BREAST-Q scores were used to perform meta-analyses on five BREAST-Q domains. Results: Thirteen comparative studies including 3895 patients were selected from 1202 articles found. Meta-analyses of the BREAST-Q domains showed a significant mean difference of 7.64 in the Sexual Well-being domain (P = 0.01) and 4.71 in the Psychosocial Well-being domain (P = 0.03), both in favor of NSM. Using the specifically designed questionnaires, no differences in overall satisfaction scores were found. There were no differences in overall complication rates between the two groups. Conclusions: Patient satisfaction scores were high after both NSM and SSM; however, NSM led to a higher sexual and psychosocial well-being. No differences in complication rates were found. In combination with other factors, such as oncologic treatments, complication risk profile, and fear of cancer recurrence, the decision for NSM or SSM has to be made on an individual basis and only if NSM is considered to be oncologically safe.

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Section: Discussionmentioning

confidence: 84%

“…The study-specific characteristics are summarized in Table 1. 5,6,17,[22][23][24][25][26][27][28][29][30][31]…”

Section: Search Resultsmentioning

confidence: 99%

Section: Study Characteristicsmentioning

confidence: 99%

Section: Study Characteristicsmentioning

confidence: 99%

mentioning

confidence: 99%

See 3 more Smart Citations

Quality of life, patient satisfaction, and complications after nipple-sparing versus skin-sparing mastectomy followed by immediate breast reconstruction. A systematic review and meta-analysis.

Clarijs

Peeters

Dongen

et al. 2023

Plastic &Amp; Reconstructive Surgery

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Trends and issues in clinical research on satisfaction and quality of life after mastectomy and breast reconstruction: a 5-year scoping review

et al. 2023

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Breast reconstruction (BR) aims to improve the satisfaction and quality of life (QOL) of breast cancer survivors. Clinical studies using patient-reported outcomes (PROs) can therefore provide relevant information to the patients and support decision-making. This scoping review was conducted to analyze recent trends in world regions, methods used, and factors investigated. The literature search was conducted in August 2022. Databases of PubMed, MEDLINE, and CINAHL were searched for relevant English-language studies published from 2017 to 2022. Studies involving women with breast cancer who underwent BR after mastectomy and investigated PROs after BR using BR-specific scales were included. Data on the country, publication year, study design, PRO measures (PROMs) used, time points of surveys, and research themes were collected. In total, 147 articles met the inclusion criteria. BREAST-Q was the most widely used, contributing to the increase in the number and diversification of studies in this area. Such research has been conducted mainly in North America and Europe and is still developing in Asia and other regions. The research themes involved a wide range of clinical and patient factors in addition to surgery, which could be influenced by research methods, time since surgery, and even cultural differences. Recent BR-specific PROMs have led to a worldwide development of research on factors that affect satisfaction and QOL after BR. PRO after BR may be influenced by local cultural and social features, and it would be necessary to accumulate data in each region to draw clinically useful conclusion.

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Updated findings of skin flap thickness and residual breast tissue after mastectomy for breast cancer: a systematic review of the literature

Lv,

Fu,

2023

Updates Surg

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Nipple reconstruction in autologous breast reconstruction after areola-sparing mastectomy

Cited by 7 publications

References 12 publications

Quality of life, patient satisfaction, and complications after nipple-sparing versus skin-sparing mastectomy followed by immediate breast reconstruction. A systematic review and meta-analysis.

Quality of life, patient satisfaction, and complications after nipple-sparing versus skin-sparing mastectomy followed by immediate breast reconstruction. A systematic review and meta-analysis.

Trends and issues in clinical research on satisfaction and quality of life after mastectomy and breast reconstruction: a 5-year scoping review

Updated findings of skin flap thickness and residual breast tissue after mastectomy for breast cancer: a systematic review of the literature

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