Nitric Oxide Detection with Glassy Carbon Electrodes Coated with Charge-different Polymer Films

Abstract

Trace amounts of nitric oxide (NO) have been determined in aqueous phosphate buffer solutions (pH=7.4) by using a glassy carbon electrode coated with three charge-different polymer films. The glassy carbon electrode was coated first with negatively charged Nafion film containing tetrakis(pentafluorophenylporphyrin) iron(III) chloride (Fe(III)TPFPP) as the NO oxidation catalyst, and then with positively charged poly(acrylamide-co-diallyldimethylammonium chloride) (PADDA) and with neutral poly(dimethylsiloxane) (silicone) at the outermost layer. This polymer-coated electrode showed an excellent selectivity towards NO against possible concomitants in blood such as nitrite, ascorbic acid, uric acid, and dopamine. All current ratios between each concomitant and NO at the cyclic voltammogram was in 10 -3 ~ 10 -4 . This type of electrode showed a detection limit of 80 nM for NO. It was speculated from the electrochemical study in methanol that high-valent oxoiron(IV) of Fe(TPFPP) participated in the catalytic oxidation of NO.

Synthesis, antiviral, cytotoxicity and antitumor evaluations of A4 type of porphyrin derivatives

“…It has long been known that porphyrin is a representative p-functional skeleton that has been actively investigated in many research areas. [1][2][3][4][5]. Porphyrins have received a great deal of interest because they show unique properties in electronics [6], photosynthesis [7], optical memories [8], photocatalysis [9], photodynamic therapy [10], and solar cells [11].…”

Synthesis and Spectroscopic and Biological Activities of Zn(II) Porphyrin with Oxygen Donors

“…The involvement of porphyrins in many biological processes and the possibility of tailoring their physical and chemical properties at the molecular level make the porphyrins and metalloporphyrins versatile synthetic base material for research areas due to their immense biological and fascinating importance in many technical applications including, but not limited to, sensors, solar cells, as catalysts [ 1 – 6 ], optical monomers [ 7 , 8 ], photocatalysts [ 9 – 12 ], photosensitizers in photodynamic therapy (PDT) [ 13 ], supramolecular chemistry [ 14 , 15 ], ionophores [ 16 ], and for the treatment of tumors and malignant tissues [ 17 ] in combination with electromagnetic radiation or radioactive emissions, as photosensitizers for dye sensitized solar cells (DSSCs) [ 18 , 19 ]. They are also regarded as nature's choice catalysts and carry out a remarkable spectrum of bioenergetics reaction ranging from photosynthetic energy transduction to generation of ammonia, regiospecific oxygen transfer (hydroxylation and epoxidation), and conversion of carbon dioxide to hydrocarbons.…”

Preparation and characterization of composite polyaniline materials for catalytic purposes

“…Among the conducting polymers, polyaniline (PANI) has been extensively studied due to its potential applications as a substrate for environmental sensors of polluting gases and catalyst support in fuel cells [1][2][3][4][5][6][7]. PANI films with a three-dimensional structure can be grown easily on different metal substrates by applying electrochemical methods [8][9][10][11][12].…”