Nitric oxide functionalized molybdenum(0) pyrazolone Schiff base complexes: thermal and biochemical study

Abstract

This work describes the thermal and biological implications of three pyrazolone-dinitrosylmolybdenum(0) complexes.

Molybdenum dinitrosyl Schiff base complexes of dehydroacetic acid and thiourea derivatives: DFT‐experimental characterization and nosocomial anti‐infectious implications

“…Upon examining the respective IR spectra of complexes, it is obvious that ν(NO) + and ν(Mo‐NO) modes confined to coordination sphere are given by two eminent bands in the range 1,789–1,745 and 1,800–1,845 cm −1 and a feeble band at 620–656 cm −1 , respectively, which are in close approximation as reported in other places . The two cis‐ NO moieties present within the complexes may be explained by referring to two ν(NO) bands in the spectra of all the nitrosyl complexes of molybdenum.…”

“…The Schiff bases synthesized from pyrone and thiosemicarbazone derivatives (Scheme ) were prepared by following the procedure reported elsewhere . Ethanol was used as a washing agent for the solid mass obtained and dried in a vacuum.…”

“…Nitrosyl complexes of Mo containing the abovementioned Schiff bases were prepared using the method (Scheme ) reported earlier . All the complexes were tested for their solubility and were found less soluble in ethanol and methanol, insoluble in water, and soluble in acetonitrile, DMSO chloroform, and DMF.…”

“…It has also been used for the synthesis of various classes of organic compounds. The nitrogen atoms appended in such molecules especially via Schiff base condensation are of great interest …”

Nitric oxide boosters as defensive agents against COVID-19 infection: an opinion

“…Also, the possible use of nitrate/nitrite metabolites together with the enzyme iNOS could act as prognostic viral infection markers (Uehara et al., 2015 ). In our conspicuous interest towards NO and NO-like molecules associated investigation (Mir et al., 2017 ; 2019 ; Mir & Maurya, 2018a , 2018b , 2018c , 2018d , 2018e ) this article describes some of the medically proven NO-releasers and some of the available NO-boosters that could be suggested as heath supplements to tackle the covid-19 effects. Also, their inclusion in the COVID-19 vaccination has also been suggested with suitable reasons.…”