Nitric Oxide Use in Neonatal and Adult Patients at Baylor University Medical Center

Nitric Oxide Does Not Reverse Pulmonary Hypertension Associated With End–Stage Liver Disease: A Preliminary Report

“…This study inspiratory limb of a breathing circuit and delivered to the investigates the reversibility of pulmonary hypertension alveoli. 7 Here it is absorbed by the capillaries supplying the by the inhalation of nitric oxide in patients under evaluventilated alveoli where it activates guanylate cyclase that ation for OLT. Ten patients with ESLD who were discovleads to an increase in cyclic 35-monophosphate that causes ered to have moderate to severe pulmonary hypertensmooth muscle relaxation and vasodilation.…”

“…Inhaled nitric hypertension and also to treat pulmonary hypertension and oxide is a potent pulmonary vasodilator without apparshunting in adult respiratory distress syndrome. 7,9 The preent systemic effects. Nitric oxide had no demonstrable transplantation evaluation of patients with ESLD and puleffect on mean pulmonary artery pressure (PAP) (37 vs. monary hypertension with nitric oxide might determine those 37 mm Hg), transpulmonary gradient (TPG) (26 vs. 26 patients that have reversible pulmonary hypertension, which mm Hg), or pulmonary vascular resistance (PVR) (295 might be an indicator of resolution following OLT.…”