“…These potential benefits however come with challenges associated with NOB outselection under cold and diluted loading conditions. While the operational strategies are well documented for sidestream applications (Gut et al, 2005;Hellinga et al, 1998;van de Graaf et al, 1996;van Loosdrecht and Salem, 2005;Wett et al, 2007), many recent studies were conducted to address these challenges for mainstream applications using nitritation/denitritation (Blackburne et al, 2008;Gao et al, 2009Gao et al, , 2014Peng et al, 2004Peng et al, , 2012Regmi et al, 2013) and deammonification Hu et al, 2013;Lotti et al, 2013;Wett et al, 2013;Winkler et al, 2011) or both (Vlaeminck et al, 2012;. Several mechanisms were identified by which the three autotrophic groups, i.e.…”