Nitro derivatives of glutethimide

Abstract

Crystallographic experiments performed on single crystals of m-nitroglutethimide [3-ethyl-3-(3'-nitrophenyl)piperidine-2,6-dione, CI3H14N204], (I), and o,p-

The Solid-State Structures of Cyclic NH Carboximides

“…204 [178], 205 [177] and 206 [179] (Figure 63) exist as simple R The remaining structure involves more complex bonding. Compound 202 [176] (Figure 62) displays primarily an imide NH to CO C(4) ribbon pattern of type B which is supplemented by an interaction of the same imide CO to an alcohol OH in a separate ribbon above or below the plane.…”

“…Of the twelve reported structures for 3,3-disubstituted glutarimides, four compounds 203 [177], 204 [178], 205 [177] and 206 [179] (Figure 63) exist as simple R 2 2 (8) dimers of pattern A. It should be noted, however, that while 203 and 204 bond using the imide 6-CO away from the substituents, compound 205 uses the more hindered 2-CO, and for compound 206 one carbonyl of each type is involved, giving an unsymmetrical dimer.…”