NITROGEN ISOLOGS OF BENZO[a]PYRENE¹

Abstract

Benzo [a]pyrene is one of the most powerful carcinogens known and is considered to be responsible for the cancerigenic properties of coal tar (1). A number of synthetic derivatives of this compound have been prepared and evaluated (2) but few nitrogen isologs have been prepared and examined for carcinogenicity or anticarcinogenicity (3). The present study was undertaken to provide addi-

Highly Fluorescent Pyreno[2,1-b]pyrroles: First Syntheses, Crystal Structure, and Intriguing Photophysical Properties

“…For further extension of pyrene systems, heterocyclic pyrene analogues such as pyreno [2,1-b]furan, 16 pyreno-[2,1-b]thiophene, 17 pyreno[2,1-b]pyridine, 18 pyreno[2,1-c]pyridine, 18 and pyreno[1,2-b]pyridine 18 have been developed. However, to our knowledge, there is no report of pyreno [2,1-b]pyrrole systems.…”