“…Based on the above III 1 –III 6 modes, the bypass of the influent around U 1 or U 2 is included to reflect the scenario of step feed in the active sludge process, ammonia stripping as pretreatment, supplement of a carbon source for denitrification, and anaerobic ammonium oxidation . Therefore, 18 modes with bypass (i.e., III 11 –III 13 , III 21 –III 23 , III 31 –III 33 , III 41 –III 43 , III 51 –III 53 , and III 61 –III 63 ) are involved for III 1 –III 6 modes to guarantee the integrality of the model, though some modes might not be commonly applied in real wastewater treatment projects.…”