Nitropyrazoles

Vinogradov, V. M.; Cherkasova, T. I.; Далингер, И. Л.; Shevelev, S. A.

doi:10.1007/bf00699193

Cited by 20 publications

(12 citation statements)

References 2 publications

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“…However, 1,4‐dinitropyrazole in the same conditions gave a mixture containing 3,5‐dinitropyrazole, unaltered 1,4‐dinitropyrazole and 4‐nitropyrazole 39. The thermodynamic properties of DNP are: melting point=86 °C, ρ =1.81 g cm −3 , Δ f H =120.1 kJ mol −1 , D =8.24 km s −1 , and P =28.80 GPa 43, 44.…”

Section: Melt Cast Explosives and Their Formulationsmentioning

confidence: 97%

Solanaceae — a model for linking genomics with biodiversity

et al. 2004

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Recent progress in understanding the phylogeny of the economically important plant family Solanaceae makes this an ideal time to develop models for linking the new data on plant genomics with the huge diversity of naturally occurring species in the family. Phylogenetics provides the framework with which to investigate these linkages but, critically, good species-level descriptive resources for the Solanaceae community are currently missing. Phylogeny in the family as a whole is briefly reviewed, and the new NSF Planetary Biodiversity Inventories project 'PBI: Solanum -a worldwide treatment' is described. The aims of this project are to provide species-level information across the global scope of the genus Solanum and to make this available over the Internet. The project is in its infancy, but will make available nomenclatural information, descriptions, keys and illustrative material for all of the approximately 1500 species of Solanum. With this project, the opportunity of linking valid, up-to-date taxonomic information about wild species of Solanum with the genomic information being generated about the economically important species of the genus (potato, tomato and eggplant) can be realized. The phylogenetic framework in which the PBI project is set is also of enormous potential benefit to other workers on Solanum. The community of biologists working with Solanaceae has a unique opportunity to effectively link genomics and taxonomy for better understanding of this important family, taking plant biology to a new level for the next century.

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Section: Melt Cast Explosives and Their Formulationsmentioning

confidence: 97%

Solanaceae — a model for linking genomics with biodiversity

et al. 2004

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“…). The additional prove came from the independent synthesis of 5a via the alkaline hydrolysis of carbamate 7 (Scheme ).…”

Section: Resultsmentioning

confidence: 99%

“…The solution of KOH (7.23g , 0.13 mol) and carbamate 7 (10 g, 0.043 mol) in H 2 O (100 mL) was heated at 80–90°C for 7 h. The resulting mixture was cooled down and left overnight. The precipitate of potassium salt was filtered off, washed with ice‐water, suspended in water, and acidified by 20% H 2 SO 4 to pH 1.…”

Section: Methodsmentioning

confidence: 99%

Synthesis and Comparison of the Reactivity of 3,4,5-1H-Trinitropyrazole and ItsN-Methyl Derivative

Далингер

Вацадзе

Шкинева

et al. 2013

J. Heterocyclic Chem.

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3,4,5‐Trinitro‐1H‐pyrazole (1) has been obtained via nitration of 3,5‐dinitropyrazole with mixture of sulfuric and nitric acids. Compound 1 reacts with excess ammonia and aliphatic amines, in the presence of bases with NH‐azoles, phenols, thiols, and triflouroethanol at mild conditions in water. All these reactions occur as the nucleophilic substitution of the nitro‐group at position 4 in 1 affording 4‐R‐3,5‐dinitropyrazoles. The product of methylation of 1, N‐methyl‐3,4,5‐trinitropyrazole (4), also reacts with thiols, phenols, oximes, ammonia, amines, and NH‐azoles. The reactions proceed with high yields but nucleophilic substitutions in these cases occur regioselectively at position 5 in 4 to afford 5‐R‐3,4‐dinitropyrazoles.

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“…This work deals with 4-amino-3,5-dinitropyrazole (1), which is an example of a pyrazole with alternating nitro and amino groups (Scheme 1). Protected 1 was first prepared by Vinogradov et al [4] in a synthesis with six steps. The parent compound 1 was later presented by Shevelev et al [5].…”

Section: Introductionmentioning

confidence: 99%

Four Syntheses of 4‐Amino‐3,5‐dinitropyrazole

Latypov

2014

Journal of Heterocyclic Chem

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in Wiley Online Library (wileyonlinelibrary.com).In this paper, syntheses of 4-amino-3,5-dinitropyrazole from four different starting materials are described. The starting materials were 4-nitropyrazole, 4-nitro-3,5-dimethylpyrazole, 3,5-dinitropyrazole, and 4-chloropyrazole, respectively. They are compared in terms of yield, number of steps and suitability for scale-up into pilot scale production. The overall yield, calculated from commercially available starting materials, ranged from 21% in the case of synthesis via 3,5-dinitropyrazole up to 61% for the one starting from 4-chloropyrazole. With numerous factors taken into account, the latter was chosen for a pilot scale study and the product could be produced in batches of 200 g.

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Nitropyrazoles

Cited by 20 publications

References 2 publications

Solanaceae — a model for linking genomics with biodiversity

Solanaceae — a model for linking genomics with biodiversity

Synthesis and Comparison of the Reactivity of 3,4,5-1H-Trinitropyrazole and ItsN-Methyl Derivative

Four Syntheses of 4‐Amino‐3,5‐dinitropyrazole

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