Nitrous oxide

Banks, A. Lawrence; Hardman, Jonathan G.

doi:10.1093/bjaceaccp/mki039

Cited by 34 publications

(25 citation statements)

References 6 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Chronic vitamin B 12 inactivation can present with symptoms ranging from mild paraesthesiae 12 to a neurological condition resembling subacute degeneration of the cord. 11 14 15 Impairment of methylation of myelin sheath proteins results in axonal loss, causing myelopathy and peripheral neuropathy.…”

Section: Problems From Chronic Usementioning

confidence: 99%

The increasing recreational use of nitrous oxide: history revisited

Randhawa

Bodenham

2016

British Journal of Anaesthesia

View full text Add to dashboard Cite

show abstract

Section: Problems From Chronic Usementioning

confidence: 99%

The increasing recreational use of nitrous oxide: history revisited

Randhawa

Bodenham

2016

British Journal of Anaesthesia

View full text Add to dashboard Cite

show abstract

“…Many investigations suggest that the use of N 2 O may be harmful because of the induced bone marrow suppression. N 2 O impairs methionine synthase activity, disturbs folate metabolism, and thus vitamin B12 metabolism 16. In addition to this, there is not enough data on N 2 O safety in patients with FA 1…”

Section: Discussionmentioning

confidence: 99%

Pregnancy after allogeneic hematopoietic stem cell transplantation in a Fanconi anemia patient

Atashkhoei¹,

Fakhari²,

Bilehjani³

et al. 2017

IMCRJ

View full text Add to dashboard Cite

Pregnancy in patients with Fanconi anemia (FA) is rare. However, there are reports of successful pregnancy in Fanconi patients after bone marrow transplantation (BMT, hematopoietic stem cell transplantation). We describe the case of a term pregnant woman with FA who was treated with BMT 2 years earlier. She underwent successful delivery with cesarean section using spinal anesthesia without any complications.

show abstract

“…It is a more soluble gas than nitrogen, in large concentrations is associated to a second gas effect, diffusion hypoxia and expansion of air-filled spaces in the body [12]. Its role has evolved greatly, since a sole anesthetic to a volatile anesthetic vehicle, and it has its place in common practice.…”

Section: Nitrous Oxidementioning

confidence: 99%

“…Nitrous oxide has several pharmacodynamic effects that include: increases respiratory rate, reduces the ventilatory response to hypoxia and hypercapnia, reduces mucociliary function and neutrophil chemotaxis, impels some myocardial depression (despite increasing sympathetic out flow), increases pulmonary vascular resistance, increases cerebral blood flow, cerebral metabolism and intracranial pressure [12]. It has analgesic effect thought to be mediated by activation of opioid receptors in the periaqueductal grey matter of the midbrain, which leads to modulation of nociception pathways and activation of α2 adrenoreceptors in the dorsal horn of the spinal cord [12].…”

Section: Nitrous Oxidementioning

confidence: 99%

See 1 more Smart Citation

O2 and N2O: Between the Rock and the Hard Place

Machado¹

2016

J Anesth Clin Res

View full text Add to dashboard Cite

The use of oxygen and nitrous oxide is part of anesthetic practice since ever. These gases follow anesthetic practice in almost all types of clinical settings, procedures and patients. Their indications and limitations of use are well known.In recent years a great debate either in literature or in scientific meetings has been addressed, concerning the potential poor outcomes related to the use of certain amounts of oxygen and the use of nitrous oxide.The objective of this review is to gather information related to these two topics, based on the recent most relevant publications (2000)(2001)(2002)(2003)(2004)(2005)(2006)(2007)(2008)(2009)(2010)(2011)(2012)(2013)(2014)(2015)(2016).Results show that both drugs have its advantages and drawbacks, and it is the clinical objective, the procedure, and the type of patient that will contribute the most for the anesthesiologist final decision.As a conclusion it was found that, 1) oxygen is a lifesaving drug on one side, but its use should be judicious since its high inspired fraction may have direct implications on that lung wellbeing, and 2) nitrous oxide has its known contraindications that should be taken into consideration and preclude its use when not clinically appropriate, however no evidence exists that indicates a formal discontinuation of its use, and in certain clinical scenarios it can be of relevant utility.

show abstract

Nitrous oxide

Cited by 34 publications

References 6 publications

The increasing recreational use of nitrous oxide: history revisited

The increasing recreational use of nitrous oxide: history revisited

Pregnancy after allogeneic hematopoietic stem cell transplantation in a Fanconi anemia patient

O2 and N2O: Between the Rock and the Hard Place

Contact Info

Product

Resources

About