NK cell receptors in anti-tumor and healthy tissue protection: Mechanisms and therapeutic advances

Greppi, Marco; De Franco, Fabiana; Obino, Valentina; Rebaudi, Federico; Goda, Rayan; Frumento, Davide; Vita, Giorgio; Baronti, Camilla; Melaiu, Ombretta; Bozzo, Matteo; Candiani, Simona; Vellone, Valerio G.; Papaccio, Federica; Pesce, Silvia; Marcenaro, Emanuela

doi:10.1016/j.imlet.2024.106932

Immunology Letters

2024

DOI: 10.1016/j.imlet.2024.106932

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NK cell receptors in anti-tumor and healthy tissue protection: Mechanisms and therapeutic advances

Marco Greppi,

Fabiana De Franco,

Valentina Obino

et al.

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2024

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Case report: A case of esophageal small cell carcinoma misdiagnosed as leiomyoma

Yan,

Xiao

2024

Front. Med.

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Primary esophageal small cell carcinoma (PESC) is a rare, extremely aggressive malignancy characterized by rapid growth, early metastasis, and poor prognosis. This study presents a case of early-stage PESC that was initially misdiagnosed as an esophageal leiomyoma, which was observed as a submucosal tumor during gastroscopy. The patient subsequently underwent endoscopic submucosal dissection (ESD), which successfully achieved complete tumor resection. Histopathological analysis later confirmed the diagnosis of small cell carcinoma. Subsequent treatments were recommended; however, the patient declined these options and developed systemic metastases 16 months later, indicating progression to advanced disease and a poor prognosis. This case underscores the imperative to consider PESC in the differential diagnosis of submucosal esophageal lesions, especially when clinical suspicion is elevated, despite its rarity. Additionally, it highlights the challenges associated with the diagnosis and management of submucosal PESC and emphasizes the crucial role of early diagnosis in enhancing patient prognosis and survival rates.

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Case report: A case of esophageal small cell carcinoma misdiagnosed as leiomyoma

Yan,

Xiao

2024

Front. Med.

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NK cell receptors in anti-tumor and healthy tissue protection: Mechanisms and therapeutic advances

Cited by 1 publication

References 168 publications

Case report: A case of esophageal small cell carcinoma misdiagnosed as leiomyoma

Case report: A case of esophageal small cell carcinoma misdiagnosed as leiomyoma

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