No. 225-Management Guidelines for Obstetric Patients and Neonates Born to Mothers With Suspected or Probable Severe Acute Respiratory Syndrome (SARS)

Maxwell, Cynthia; McGeer, Allison; Tai, Kin Fan Young; Sermer, Mathew

doi:10.1016/j.jogc.2017.04.024

Cited by 84 publications

(81 citation statements)

References 34 publications

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“…According to the No. 225 Management Guidelines for Obstetric Patients and Neonates Born to Mothers With Suspected or Probable SARS [16], we took strict measures to reduce the risk of infection. The male infant in the case reported was delivered by emergency cesarean under contact, droplet, and airborne transmission precautions [17].…”

Section: Discussionmentioning

confidence: 99%

A Case Report of Neonatal 2019 Coronavirus Disease in China

Wang

Guo

Ling

et al. 2020

Clinical Infectious Diseases

469

533

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In December 2019, the coronavirus disease (COVID-19) caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged in China and now has spread in many countries. Pregnant women are a population susceptible to COVID-19 and are more likely to have complications and even progress to severe illness. We report a case of neonatal COVID-19 in China with pharyngeal swabs testing positive by real-time reverse-transcription polymerase chain reaction assay 36 hours after birth. However, whether the case is a vertical transmission from mother to child remains to be confirmed.

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Section: Discussionmentioning

confidence: 99%

A Case Report of Neonatal 2019 Coronavirus Disease in China

Wang

Guo

Ling

et al. 2020

Clinical Infectious Diseases

469

533

View full text Add to dashboard Cite

show abstract

“…The clinical outcomes among pregnant women with SARS in Hong Kong were worse than those occurring in infected women who were not pregnant [32]. Wong et al [29] evaluated the obstetrical outcomes from a cohort of pregnant women who developed SARS in Hong Kong during the period of 1 February to 31 July 2003.…”

Section: Sars and Pregnancymentioning

confidence: 99%

“…Maxwell et al [32] reported 7 pregnant women infected with SARS-CoV who were followed at a designated SARS unit-2 of the 7 died (CFR of 28%), and 4 (57%) required ICU hospitalization and mechanical ventilation. In contrast, the mortality rate was less than 10% and mechanical ventilation rate less than 20% among non-pregnant, age-matched counterparts who were not infected with SARS-CoV.…”

Section: Sars and Pregnancymentioning

confidence: 99%

Potential Maternal and Infant Outcomes from Coronavirus 2019-nCoV (SARS-CoV-2) Infecting Pregnant Women: Lessons from SARS, MERS, and Other Human Coronavirus Infections

Schwartz

Graham

2020

Viruses

923

862

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In early December 2019 a cluster of cases of pneumonia of unknown cause was identified in Wuhan, a city of 11 million persons in the People's Republic of China. Further investigation revealed these cases to result from infection with a newly identified coronavirus, initially termed 2019-nCoV and subsequently SARS-CoV-2. The infection moved rapidly through China, spread to Thailand and Japan, extended into adjacent countries through infected persons travelling by air, eventually reaching multiple countries and continents. Similar to such other coronaviruses as those causing the Middle East respiratory syndrome (MERS) and severe acute respiratory syndrome (SARS), the new coronavirus was reported to spread via natural aerosols from human-to-human. In the early stages of this epidemic the case fatality rate is estimated to be approximately 2%, with the majority of deaths occurring in special populations. Unfortunately, there is limited experience with coronavirus infections during pregnancy, and it now appears certain that pregnant women have become infected during the present 2019-nCoV epidemic. In order to assess the potential of the Wuhan 2019-nCoV to cause maternal, fetal and neonatal morbidity and other poor obstetrical outcomes, this communication reviews the published data addressing the epidemiological and clinical effects of SARS, MERS, and other coronavirus infections on pregnant women and their infants. Recommendations are also made for the consideration of pregnant women in the design, clinical trials, and implementation of future 2019-nCoV vaccines.Viruses 2020, 12, 194 2 of 16 tract infections. Both the SARS-CoV and MERS-CoV have several features in common that are factors in producing nosocomial transmission, replication in the lower respiratory tract, and viral immunopathology. Both coronaviruses are zoonotic infections and constitute significant public health threats that have resulted in epidemics with significant loss of life [1,5,6]. When the SARS-CoV and MERS-CoV infect women who are pregnant, they can result in poor obstetric outcomes including maternal morbidity and death. There are currently no vaccines or specific treatments approved for coronavirus infections [2,6].Prior to December 2019, there were a total of six coronavirus species that produced human infection: HCoV-229E and HCoV-NL63 belonging to the Alphacoronavirus genus; and HCoV-OC43, HCoV-HKU1, MERS-CoV, and SARS-CoV, which belong to the Betacoronavirus genus [1,2]. As of December 2019, there are now seven species that infect humans.As the newly identified novel coronavirus, termed 2019-nCoV and subsequently named SARS-CoV-2, spreads rapidly throughout China and across to other countries, researchers scramble to understand transmission dynamics, virulence, and pathogenicity. Given the rapidly progressive spread of this current 2019 novel coronavirus it is reasonable to expect that pregnant women have already become infected. The effect of 2019-nCoV during pregnancy is, at the present, unknown. This communication reviews the medical ...

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“…Two infected mothers recovered and maintained their pregnancy but had infants with intrauterine growth restriction (IUGR). Among the live newborn infants, none had clinical or laboratory evidence for SARS-CoV infection [18]. Ng et al, in a study evaluated the placental pathology in seven pregnant women infected with SARS-CoV.…”

Section: Mers-cov or Sars-covmentioning

confidence: 99%