2021
DOI: 10.1007/s10393-021-01569-1
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No Evidence of SARS-CoV-2 Infection in Neotropical Primates Sampled During COVID-19 Pandemic in Minas Gerais and Rio Grande do Sul, Brazil

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Cited by 6 publications
(9 citation statements)
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“…NHP, including common marmosets (C. jacchus) has been extensively used as experimental models for SARS-COV-2 and others respiratory coronavirus (MERS-COV and SARS-COV), reproducing the disease that is observed in human patients (70,104,166,201,213). Therefore, two studies were performed searching for evidence of SARS-COV-2 in free-ranging NWP populations from the genera Callithrix, Callicebus, and Alouatta, all from hotspots for COVID-19 in Brazil (2,175). A total of 111 NWP was evaluated by RT-qPCR of oral and nasal swabs, blood and/or tissues and by PRNT, but no SARS-CoV-2 positive samples were detected, regardless of NWP species or biome tested (2,175), raising questions about the susceptibility of these animals to SARS-COV-2 under natural conditions.…”
Section: Severe Acute Respiratory Syndrome Coronavirus 2 (Sars-cov-2)mentioning
confidence: 99%
“…NHP, including common marmosets (C. jacchus) has been extensively used as experimental models for SARS-COV-2 and others respiratory coronavirus (MERS-COV and SARS-COV), reproducing the disease that is observed in human patients (70,104,166,201,213). Therefore, two studies were performed searching for evidence of SARS-COV-2 in free-ranging NWP populations from the genera Callithrix, Callicebus, and Alouatta, all from hotspots for COVID-19 in Brazil (2,175). A total of 111 NWP was evaluated by RT-qPCR of oral and nasal swabs, blood and/or tissues and by PRNT, but no SARS-CoV-2 positive samples were detected, regardless of NWP species or biome tested (2,175), raising questions about the susceptibility of these animals to SARS-COV-2 under natural conditions.…”
Section: Severe Acute Respiratory Syndrome Coronavirus 2 (Sars-cov-2)mentioning
confidence: 99%
“…A possibilidade de zoonose reversa para grandes símios, incluindo chimpanzés e gorilas, ensejou a implementação de medidas de proteção em reservas de vida selvagem em toda a África e Ásia (Gibbons, 2021). Macacos não-primatas do novo mundo apresentam baixa susceptibilidade ao SARS-CoV-2 (Lu et al, 2020;, possivelmente pela menor afinidade do receptor ACE2, que apresenta similitude de 92% em relação ao receptor celular de humanos, com quatro diferenças entre os doze locais de ligação considerados essenciais para o acoplamento do SARS-CoV-2 (Melin et al, 2020;Bhattacharkjee et al, 2021;Abreu et al, 2021). Pesquisas realizadas no Brasil com macacos de vida livre não encontraram sinais de infecções nesses animais (Sacchetto et al, 2020;Abreu et al, 2021).…”
Section: O Vison Europeu (Mustela Vison) E O Vison Americano (Neoviso...unclassified
“…In the Americas, there is great concern about the risks of SARS-CoV-2 transmission from humans to wildlife, including neotropical non-human primates ( Abreu et al , 2021 ). Previous molecular and serological studies have demonstrated no evidence of natural SARS-CoV-2 infection in non-human primates from urban, rural or sylvatic habitats ( Abreu et al , 2021 ; Sacchetto et al , 2021 ).…”
mentioning
confidence: 99%
“…In the Americas, there is great concern about the risks of SARS-CoV-2 transmission from humans to wildlife, including neotropical non-human primates ( Abreu et al , 2021 ). Previous molecular and serological studies have demonstrated no evidence of natural SARS-CoV-2 infection in non-human primates from urban, rural or sylvatic habitats ( Abreu et al , 2021 ; Sacchetto et al , 2021 ). However, the explosive spread of SARS-CoV-2 in areas where contact between humans and native fauna is frequent increases the need for surveillance for early identification and response to the potentially harmful effects ( Gryseels et al , 2020 ).…”
mentioning
confidence: 99%