No Influence of Nonivamide-nicoboxil on the Peak Power Output in Competitive Sportsmen

Abstract

Recent studies have shown that the oxygenated hemoglobin level can be enhanced during rest through the application of nonivamide-nicoboxil cream. However, the effect of nonivamide-nicoboxil cream on oxygenation and endurance performance under hypoxic conditions is unknown. Therefore, the purpose of this study was to investigate the effects of nonivamide-nicoboxil cream on local muscle oxygenation and endurance performance under normoxic and hypoxic conditions. In a cross-over design, 13 athletes (experienced cyclists or triathletes [age: 25.2±3.5 years; VO2max 62.1±7.3 mL·min−1·kg−1]) performed four incremental exercise tests on the cycle ergometer under normoxic or hypoxic conditions, either with nonivamide-nicoboxil or placebo cream. Muscle oxygenation was recorded with near-infrared spectroscopy. Capillary blood samples were taken after each step, and spirometric data were recorded continuously. The application of nonivamide-nicoboxil cream increased muscle oxygenation at rest and during different submaximal workloads as well as during physical exhaustion, irrespective of normoxic or hypoxic conditions. Overall, there were no significant effects of nonivamide-nicoboxil on peak power output, maximal oxygen uptake or lactate concentrations. Muscle oxygenation is significantly higher with the application of nonivamide-nicoboxil cream. However, its application does not increase endurance performance.

Muscle Oximetry in Sports Science: An Updated Systematic Review

“…as a means of enhancing muscle performance or recovery). The following situations were compared with some control scenarios to evaluate the muscle oxygenation responses and the potential benefits of the tested product or intervention: the use of a tracksuit jacket with heating elements [ 162 ], nonivamide-nicoboxil cream [ 180 ], sports compression garment ( n = 3 for lower limb: tights, calf sleeve, socks; n = 1 for upper limb, forearm) [ 18 , 19 , 31 , 107 ], core and skin cooling [ 136 ], undergoing thigh cooling by a water-circulating pad [ 85 ] and oral supplementation with dietary inorganic nitrate-rich and placebo beetroot juice [ 32 , 33 , 40 , 43 , 63 , 75 , 76 , 131 , 146 , 158 , 183 , 190 , 201 ], supplementation with pomegranate extract and co-supplementation with N -acetylcysteine [ 39 ], protein powder [ 134 ], pre-exercise ingestion of a drink with higher dissolved O 2 [ 135 ], anthocyanin-rich New Zealand blackcurrant supplementation [ 27 ], 1 h after a single dose of mango leaf extract rich in mangiferin and lecithin, or mango leaf extract rich in mangiferin and quercetin, phospholipids addition [ 53 – 55 ], red spinach extract [ 121 ], citrulline drink/citrulline malate [ 190 , 196 ], l -arginine [ 141 , 143 ], Montmorency cherry polyphenols [ 67 ], eicosapentaenoic acid and docosahexaenoic acid (fish oil) [ 198 ], caffeine intake [ 189 ] and dark chocolate [ 81 ].…”

Effect of Topical Sports Cream Containing Cymbopogon schoenanthus on Acute Recovery Markers Following Exercise-Induced Muscle Fatigue in Competitive Athletes: A Pilot Study

“…The characteristics of sports creams can be considered the cause of this change. Sports cream is a blood-circulation-promoting cream that produces heat [28]. Previous studies have shown a significant increase in tissue blood flow when heat wraps are used [29].…”