“…185 Eight studies included patients aged ≥ 50 years; 87,98,103,118,173,187,188,192 18 studies included patients aged ≥ 60 years; 12,89,96,104,114,117,119,122,132,133,149,154,164,[193][194][195][196][197] 19 studies included patients aged ≥ 70 years; 69,72,79,88,106,108,110,111,116,120,131,136,143,148,150,161,180,183,184 and seven studies included patients aged ≥ 80 years. 13,81,123,134,137,152,178 The age of the included participants could not be determined from the study reports for four studies.…”