Welcome to this issue of European Surgery. Present times ask for short, brief and focused approaches. We have run out of time, space and attention. There is not much time left for the surgeon to read, listen and learn. There is a lot of work to be done. Routine calls for increased respect, tolerance and understanding. Productive and highly stimulating management has to react to meet the requirements of our present episode of humankind. The interaction between a natural phenomenon and the inventions and achievements of man tailor a new life for all of us-you and me and your friends, neighbours and families. Cultures call for positive vibrations. May we offer the fascinating harmonic sound of a new age.Going in line with these suggestions, this issue of European Surgery orchestrates a topic related to an important and frequently treated condition: the surgical and interventional management of biliodigestive and gall bladder disease. The editor of the topic, Professor Hans-Jörg Mischinger, Graz, Styria, Austria, and the authors are to be congratulated for this beautiful, well-tuned temper of knowledge and the straightforward presentation of recent evidence. May the papers foster a better understanding and contribute to ease your surgical routine.Our life is all about changes and processes and alterations of states of mood, tune, temper and atmosphere [1][2][3][4]. As such we have to learn to deal with the translation of actual issues and states of affairs which are new to us, which have not been seen before (at least by us!). Novelty counts our power, strength and