No time for complacency on COVID-19 in Europe

Flahault, Antoine; Calmy, Alexandra; Costagliola, Dominique; Драпкина, О. М.; Eckerle, Isabella; Larson, Heidi; Legido‐Quigley, Helena; Noakes, Catherine; Kazatchkine, Michel D.; Kluge, Hans

doi:10.1016/s0140-6736(23)01012-7

Cited by 14 publications

(12 citation statements)

References 13 publications

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“…In late 2021, a worldwide resurgence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) occurred with the rapid spread of the Omicron variant. In 2022, the considerable reduction in coronavirus disease (COVID-19) hospitalisation and mortality compared with the early phase of the pandemic was attributable to broad access to COVID-19 vaccines, SARS-CoV-2 infection and reinfection acquired immunity, 1 , 2 , 3 , 4 , 5 , 6 attenuated viral pathogenicity of Omicron, 7 , 8 increased availability of effective treatments such as neutralising monoclonal antibodies and antivirals, 9 , 10 and the advent of bivalent COVID-19 vaccine boosters. 11 Yet in the UK, COVID-19 accounted for 3.9% of all deaths in 2022 with a total of 12,017 deaths from January to May 2023.…”

Section: Introductionmentioning

confidence: 99%

“…In particular, COVID-19 remains a threat for immunocompromised individuals, owing to their suboptimal response to vaccines 18 , 19 , 20 and the lifting of non-pharmaceutical preventive public health measures. 6 In immunocompromised individuals, COVID-19 vaccines elicit shorter duration of protection, 21 lower seroconversion rates post-vaccination, 21 , 22 , 23 and reduced neutralisation activity. 22 Immunocompromised individuals may consequently be at increased risk of hospitalisation and death even after vaccination.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Impact of COVID-19 on immunocompromised populations during the Omicron era: insights from the observational population-based INFORM study

Evans,

Dube,

et al. 2023

The Lancet Regional Health - Europe

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Impact of COVID-19 on immunocompromised populations during the Omicron era: insights from the observational population-based INFORM study

Evans,

Dube,

et al. 2023

The Lancet Regional Health - Europe

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“…A significant decline in diagnostic testing across the continent makes it challenging to evaluate the scope of the most recent COVID-19 waves [ 5 - 7 ]. Various findings across the USA and Europe have exhibited that after adjusting for variables, the rate of previous exposure to SARS-CoV-2, which was characterized by seropositivity, surpassed the incidence of reported cases by at least 10 times [ 4 , 8 , 9 ]. Numerous studies have attempted to decipher the epidemiological profile and features of the virus.…”

Section: Introductionmentioning

confidence: 99%

SARS-CoV-2 Pandemic: A Comparison Between the Epidemiological Situation in Greece and Romania

Rigatou,

Sultana

2024

Cureus

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Introduction Since the onset of the SARS-CoV-2 pandemic, there seems to be scarce data targeting the comparison of epidemiological data among different countries. In an attempt to reveal and characterize the epidemiological profile in the Balkan peninsula, a cross-sectional study has been conducted, aiming to retrospectively collect all the existing information regarding the SARS-CoV-2 pandemic over a period of three years, starting from March 2020 until March 2023. The comparative analysis of the epidemiological features and the main indicators between Romania and Greece can generate a good overview of the factors that can influence public health and create an adequate system of measures to limit the COVID-19 pandemic in the area. A retrospective comparative study aiming to detect and associate the main indicators determining the evolution of the SARS-CoV-2 pandemic data with the control measures adopted in Romania and Greece was performed. Methods Publicly available data were obtained from official sources such as the World Health Organization, the European Centre for Disease Control, the Romanian and Greek Ministries of Health, and the Romanian National Centre for Surveillance and Control of Communicable Diseases. The reported number of cases, in total and in conjunction with the age distribution, total number of deaths, and vaccination coverage, from the onset of the pandemic in March 2020 until March 2023, were collected. All officially reported cases of COVID-19 were included in this analysis. Reports with missing or incomplete values regarding the timeframe, age distribution, and vaccination status were excluded. Results During the timeframe of the study, from March 2020 until March 2023, Greece reported a higher number of confirmed SARS-CoV-2 cases as compared to Romania (5,910,103 cases and 3,352,356 cases, respectively). Still, in terms of the overall death toll, Romania recorded a higher mortality rate than Greece during the pandemic (67.773 deaths vs. 36.372 deaths). Concerning both cumulative incidence rates and the 14-day case notification rate per 100.000 inhabitants, it is evident that Romania exhibited greater numbers throughout the course of the pandemic. Although it is not clearly stated, the compulsory vaccination of elderly people that was set as a high priority in Greece may have contributed to the above results. In terms of the 14-day death notification rate per 100.000 inhabitants in 2020 and 2021, Romania showed a higher rate than Greece, while Greece reported a greater rate in 2022 and up until March 2023. Between 2020 and 2023, Greece presented both a higher number of vaccinated individuals and a higher vaccination coverage with two doses (7,034,695 individuals, 70% of the general population), as compared to Romania (6,467,804 individuals, 33.68% of the general population, p<0.0001). Conclusions Despite the similar restrictions and preventive actions...

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“…Currently, the world is experiencing persistent outbreaks of this disease on a global scale. [1][2][3] Although vaccines can effectively enhance the population's resistance to the virus and reduce the mortality rate among patients, the continuous mutation of the virus leads to immune escape. 4,5 As a result, even individuals who have previously been infected with COVID-19 can still experience reinfection.…”

Section: Introductionmentioning

confidence: 99%

sTREM-1 as a Predictive Biomarker for Disease Severity and Prognosis in COVID-19 Patients

Geng,

Wu,

Liu

et al. 2024

JIR

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No time for complacency on COVID-19 in Europe

Cited by 14 publications

References 13 publications

Impact of COVID-19 on immunocompromised populations during the Omicron era: insights from the observational population-based INFORM study

Impact of COVID-19 on immunocompromised populations during the Omicron era: insights from the observational population-based INFORM study

SARS-CoV-2 Pandemic: A Comparison Between the Epidemiological Situation in Greece and Romania

sTREM-1 as a Predictive Biomarker for Disease Severity and Prognosis in COVID-19 Patients

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