Nocardia Transvalensis Pneumonia in a Child

Baghdadlian, H; Sorger, S.; Knowles, Kim; McNeil, Michael M.; J, Brown

doi:10.1097/00006454-198907000-00012

Cited by 13 publications

(7 citation statements)

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“…identified as causing invasive pulmonary and cutaneous infections. Patients with disseminated and potentially fatal N. brasiliensis (551), N. otitidiscaviarum (75,101), N. transvalensis (29,382,384), N.…”

Section: Epidemiologic Aspects Of Infection In Humansmentioning

confidence: 99%

The medically important aerobic actinomycetes: epidemiology and microbiology

1994

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The aerobic actinomycetes are soil-inhabiting microorganisms that occur worldwide. In 1888, Nocard first recognized the pathogenic potential of this group of microorganisms. Since then, several aerobic actinomycetes have been a major source of interest for the commercial drug industry and have proved to be extremely useful microorganisms for producing novel antimicrobial agents. They have also been well known as potential veterinary pathogens affecting many different animal species. The medically important aerobic actinomycetes may cause significant morbidity and mortality, in particular in highly susceptible severely immunocompromised patients, including transplant recipients and patients infected with human immunodeficiency virus. However, the diagnosis of these infections may be difficult, and effective antimicrobial therapy may be complicated by antimicrobial resistance. The taxonomy of these microorganisms has been problematic. In recent revisions of their classification, new pathogenic species have been recognized. The development of additional and more reliable diagnostic tests and of a standardized method for antimicrobial susceptibility testing and the application of molecular techniques for the diagnosis and subtyping of these microorganisms are needed to better diagnose and treat infected patients and to identify effective control measures for these unusual pathogens. We review the epidemiology and microbiology of the major medically important aerobic actinomycetes.

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Section: Epidemiologic Aspects Of Infection In Humansmentioning

confidence: 99%

The medically important aerobic actinomycetes: epidemiology and microbiology

1994

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confidence: 99%

“…Infections with this microorganism were recently reviewed by McNeil et al (382). Initially recognized as a cause of mycetoma, N. transvalensis was also recently reported to cause life-threatening invasive and disseminated infections in severely immunocompromised patients (29,382,384). No environmental source for N. transvalensis has yet been identified.…”

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confidence: 99%

The medically important aerobic actinomycetes: epidemiology and microbiology.

McNeil

Brown

1994

Clinical Microbiology Reviews

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“…To date, the few reported cases of N. transvalensis pulmonary infection have all involved immunocompromised patients [3][4][5]. This patient did have a remote history of rectal cancer, but she had been treated successfully with no noted recurrences.…”

Section: Discussionmentioning

confidence: 87%

“…Other Nocardia species are only rarely isolated from clinical specimens. Since the first report of Nocardia transvalensis infection in 1927 [2], the few reports of N. transvalensis pulmonary infections have all involved immunocompromised patients [3][4][5]. To our knowledge, this is the first report of a N. transvalensis pulmonary infection in an immunocompetent patient.…”

Section: Introductionmentioning

confidence: 87%