Nocardial epidural abscess of the thoracic spinal cord and review of the literature

Atalay, Başar; Çekinmez, Melih; Caner, Hakan; Azap, Özlem Kurt; Haberal, Mehmet

doi:10.1007/s10156-005-0384-0

Cited by 11 publications

(14 citation statements)

References 9 publications

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“…Two of the patients in this review died from disseminated infection (18%) 10 18. Five patients (45%) had complete recovery,7 12–14 two patients (18%) required assistance with walking,16 17 one patient did not have neurological recovery like our patient and one patient's outcome was not reported 8 15…”

Section: Discussionmentioning

confidence: 72%

“…Diabetes mellitus was present in two patients,7 10 alcoholism was present in two patients,9 16 intravenous drug use in one patient,15 renal failure and history of renal transplant was present in one patient 7. Chronic obstructive pulmonary disease (COPD) was reported a risk factor for pulmonary nocardiosis and was present in one patient who had pulmonary nocardiosis that spread to his spine 16…”

Section: Discussionmentioning

confidence: 99%

“…Prednisone use probably activated an old dormant infection. N asteroides was reported in nine cases 7 10 12–18 . Nocardia fracinicia was reported in one case 9.…”

Section: Discussionmentioning

confidence: 99%

“…Laminectomy was required in six patients (50%) 3 10 12 15–17. Drainage and debridement was performed in two patients 7 14. Case series and reviews reported a death rate of 18%–33% for patients with chronic nocardiasis and 66–72% for acute infections 1 4.…”

Section: Discussionmentioning

confidence: 99%

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Nocardia brasiliensisvertebral osteomyelitis and epidural abscess

Johnson

Ammar

2013

BMJ Case Reports

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Nocardia species exist in the environment as a saprophyte; it is found worldwide in soil and decaying plant matter. They often infect patients with underlying immune compromise, pulmonary disease or history of trauma or surgery. The diagnosis of nocardiosis can be easily missed as it mimics many other granulomatous and neoplastic disease. We report a 69-year-old man who presented with chronic back pain and paraparesis. He was found to have Nocardial brasiliensis vertebral osteomyelitis and epidural abscess. Laminectomy and epidural wash out was performed but with no neurological recovery. This is the second reported case of N brasiliensis vertebral osteomyelitis in the literature.

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Section: Discussionmentioning

confidence: 72%

Section: Discussionmentioning

confidence: 99%

“…Prednisone use probably activated an old dormant infection. N asteroides was reported in nine cases 7 10 12–18 . Nocardia fracinicia was reported in one case 9.…”

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Nocardia brasiliensisvertebral osteomyelitis and epidural abscess

Johnson

Ammar

2013

BMJ Case Reports

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“…22 Solitary involvement of the spinal cord, on the other hand, is very rare, and only very few cases have been reported. 1,[6][7][8]12,13,21 Spinal abscesses are more frequently found in the lower spinal levels. Only 2 other cases involved a cervical abscess localization, and in both cases, the patients died quickly after diagnosis.…”

Section: Discussionmentioning

confidence: 99%

Multiple nocardial abscesses of the brainstem and spinal cord diagnosed after an open biopsy through a cervical partial central corpectomy: case report

Peeters¹,

Vandecasteele²,

Janssen

et al. 2015

SPI

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Nocardiosis of the central nervous system is a challenging and difficult diagnosis for the clinician. The combination of infections of the brain and spinal cord is even more rare. The authors report on a patient with multiple lesions in the brainstem and cervical spinal cord. This 81-year-old immunocompetent woman presented with symptoms of progressive walking difficulty and ataxia. The results of an extensive workup with laboratory investigation, MRI, lumbar puncture, positron emission tomography (PET), and bone marrow biopsy remained inconclusive. Only after an open biopsy of a cervical lesion by an anterior approach through a partial central corpectomy of the cervical spine, was the diagnosis of nocardiosis made, allowing for specific antibiotic treatment.

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Spinal Epidural Abscess

Krishnamohan

Berger

2014

Curr Infect Dis Rep

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Spinal epidural abscess (SEA) remains a relatively infrequent diagnosis. Staphylococcus aureus is the most common organism identified, and the infectious source in SEA emanates from skin and soft tissue infections in about 20 % of instances. The thoracic spine is most often involved followed by the lumbar spine. The classic triad of fever, spinal pain, and neurological deficit is present in but a minority of patients. The appearance of neurological deficits with SEA has a significant impact on the prognosis; therefore, early diagnosis is imperative. Magnetic resonance imaging has permitted earlier diagnosis, although significant delays in diagnosis are common due to the nonspecific symptoms that frequently attend the disorder. Due to the rarity of this condition, there have been few randomized controlled trials to evaluate new treatment strategies, and most recommendations regarding treatment are based on case series studies often derived from the experiences at a single center.

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Nocardial epidural abscess of the thoracic spinal cord and review of the literature

Cited by 11 publications

References 9 publications

Nocardia brasiliensisvertebral osteomyelitis and epidural abscess

Nocardia brasiliensisvertebral osteomyelitis and epidural abscess

Multiple nocardial abscesses of the brainstem and spinal cord diagnosed after an open biopsy through a cervical partial central corpectomy: case report

Spinal Epidural Abscess

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