Nocardial infection in Crete, Greece: Review of fifteen cases from 2003 to 2007

Maraki, Sofia; Scoulica, Effie; Nioti, Eleni; Tselentis, Yannis

doi:10.1080/00365540802651905

Cited by 15 publications

(13 citation statements)

References 22 publications

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“…However, antimicrobial susceptibility patterns differ widely among Nocardia species 10 22. Multiple small studies have compared the susceptibility profile of N. abscessus to other Nocardia species 16 19–21 23 24. These have shown that N. abscessus is usually sensitive to TMP/SMX,19–21 though resistant isolates of N. abscessus have been reported 25.…”

Section: Discussionmentioning

confidence: 99%

Unusual presentation of disseminatedNocardia abscessusinfection in a patient with AIDS

et al. 2016

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A 40-year-old man with AIDS presented with symptoms of a chronic cough, subacute headache, generalised weakness with falls, urinary and faecal incontinence, and acute onset subcutaneous nodules. A chest CT scan showed multiple cavitary and nodular pulmonary infiltrates. MRI of his brain and spinal cord revealed innumerable ring-enhancing lesions. Pathological examination of the purulent material obtained from his subcutaneous lesions, as well as transbronchial tissue specimens obtained by biopsy, revealed beaded and branching Gram-positive rods, subsequently identified by 16S RNA sequencing to be Nocardia abscessus species. We observed an excellent therapeutic response to a combination antimicrobial therapy with resolution of the subcutaneous, pulmonary and central nervous system (CNS) lesions. Infections caused by N. abscessus are rare and typically occur in immunocompromised patients. In this article, we will review the presentation, diagnosis and treatment of N. abscessus infection.

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Section: Discussionmentioning

confidence: 99%

Unusual presentation of disseminatedNocardia abscessusinfection in a patient with AIDS

et al. 2016

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“…abscessus infection is thought to be rare in humans. N. abscessus infection is the cause of 15-18% of nocardiosis cases [7][8][9]. In a retrospective study over 7 years (1997-2003) including 27 clinical isolates of Nocardia spp., 6 (22%) were identified as N. abscessus [10].…”

Section: Discussionmentioning

confidence: 99%

Nocardia abscessus brain abscess in an immunocompetent host

Tawfiq

Mayman²,

Memish³

2013

Journal of Infection and Public Health

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Nocardia brain abscesses typically occur in immunocompromised patients. Most cases of nocardiosis are caused by the Nocardia asteroides complex and Nocardia brasiliensis. Here, we present a patient with a Nocardia abscessus brain abscess. The diagnosis was confirmed by DNA sequencing, and the organism was susceptible to linezolid, clarithromycin, ceftriaxone, imipenem, tobramycin, amikacin, minocycline and sulfamethoxazole. The patient was successfully treated medically in combination with surgical excision.

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“…Nokardiya tedavisinde kullanı-lan trimetoprim-sülfametoksazol, minosiklin, üçüncü kuşak sefalosporinler ve kinolonlar gibi antibiyotiklere karşı giderek artan direnç oranları, nokardiya tedavisinde tigesiklin ve linezolid gibi yeni antibiyotiklerin kullanımını gündeme getirmiştir. Ayrıca nokardiya izolatlarının kullanılan bu yeni antibiyotiklere duyarlı olduğu gösterilmiştir (18). İmmünsupresyonu, yaygın hastalığı veya santral sinir sistemi tutulumu olan hastalar ve ciddi olgularda kombinasyon tedavisi önerilmektedir (19,20).…”

Section: şEkil 4a Ve B: Etrafı Nekroz Alanları Ve Inflamatuar Hücreleunclassified

Pulmonary Nocardiosis: An Unusual Cause of Pulmonary Cavitations

Kuluöztürk¹,

Deveci²,

İn³

et al. 2017

Respir Case Rep

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ÖzetNokardiyoz, oldukça nadir görülen ve özellikle immünsüpresif olgularda ortaya çıkan fırsatçı bir enfeksiyondur. Ancak enfekte olan olguların yaklaşık üçte birinin immün sisteminin normal olduğu bilinmektedir. Nokardiyozun klinik tablosu çok geniş bir yelpazede oluşmakta ve bu nedenle diğer enfeksiyonlar hatta maligniteler ile bile karışabilmektedir. Patognomonik bulgusu, semptom ve radyolojik özellikleri olmayan bu hastalığın tanısı bazen güç olabilmektedir. Herhangi bir immünsüpresif hastalık ya da tedavi öyküsü olmayan olgumuz, nefes darlığı, halsizlik ve ateş yakınmaları ile başvurdu. Kliniğimize pnömoni ve parapnömonik efüzyon ön tanıları ile yatırıldı. Baş-langıçta non-spesifik antibiyotik tedaviye yanıt vermesine rağmen, tekrarlayan pnömoni, beraberinde sağ kolda vena sefalica ve vena basilicada trombüs ile seyreden pulmoner nokardiyazis olgusu, nadir görül-mesi ve tanı koymadaki zorluklar nedeni ile sunulmuştur. Anahtar Sözcükler: Pulmoner nokardiyoz, kavite, pnömoni, akciğer. AbstractNocardiosis is an uncommon opportunistic infection which particularly seen in immunosuppressed patients, although approximately one-third of infected patients are immunocompetent. It has a broad range of clinical presentations and may present similarly to several other infections and malignancies. The diagnosis can be challenging due to the lack of pathognomonic signs, symptoms, and radiological findings. Herein, we report a rare case of pulmonary nocardiosis in a patient who had a thrombus in the right arm vena cephalica and vena basilica of the right arm and was admitted with dyspnea, weakness, and fever without any immunosuppressive disease or treatment. The patient was hospitalized with a preliminary diagnosis of pneumonia and parapneumonic effusion, and responded to antibiotherapy.

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Nocardial infection in Crete, Greece: Review of fifteen cases from 2003 to 2007

Cited by 15 publications

References 22 publications

Unusual presentation of disseminatedNocardia abscessusinfection in a patient with AIDS

Unusual presentation of disseminatedNocardia abscessusinfection in a patient with AIDS

Nocardia abscessus brain abscess in an immunocompetent host

Pulmonary Nocardiosis: An Unusual Cause of Pulmonary Cavitations

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