Nociceptive stimuli responses at different levels of general anaesthesia and genetic variability

Abstract

This exploratory study suggests genes that may be tested further with relation to nociceptive response during anaesthesia. SC and CSS may be useful tools for monitoring nociceptive response during general anaesthesia.

Skin conductance as a pain assessment tool during chest tube removal: An observational study

“…Thus, Gjerstad et al (2007) and Storm et al (2013) showed that SCR increased after the stimulus. Thus, Gjerstad et al (2007) and Storm et al (2013) showed that SCR increased after the stimulus.…”

“…Some of the studies were performed during general anaesthesia using a tetanic stimulation as a calibrated painful stimulus. Thus, Gjerstad et al (2007) and Storm et al (2013) showed that SCR increased after the stimulus. On the opposite, Sabourdin et al (Sabourdin et al, 2013) reported that it was not modified in a similar experiment performed in children, but they used a threshold to analyse SCR which was not in accordance with the recommendations from the manufacturer (Storm, 2013).…”

Preterm infants’ behaviors and skin conductance responses to nurse handling in the NICU

“…Studies have demonstrated that the biological measures of respiration and heart rate increase in infants as a response to noxious stimuli 21 . However, fluctuations in these parameters may also be influenced by other factors such as alterations in blood circulation, breathing patterns, environmental temperature, or sedatives 8 .…”

“…However, fluctuations in these parameters may also be influenced by other factors such as alterations in blood circulation, breathing patterns, environmental temperature, or sedatives 8 . Increased skin conductance on palms and plantar surfaces has been identified as a biological measure that can validate pain perception from noxious stimuli in infants, due to increased sympathetic activity, which is more specifically associated to emotional distress than RR and HR 21 . Gjerstad et al 22 found a significant correlation between SCR/sec and the COMFORT sedation score that increased from before to during suctioning from the trachea (r= 0.78, p<0.001), while other physiologic measures did not correlate with the COMFORT sedation score.…”

Assessment of Chronic Pain: Domains, Methods, and Mechanisms

“…86 Similarly, skin conductance has been used as a measure of response to nociceptive stimuli in anesthetized women. 81 While these types of autonomic measures can be useful component of pain assessment, they are nonspecific and should not supplant self-report measures when they can be obtained.…”