Nocturnal enuresis in children

Norfolk, Sally; Wootton, Janet

doi:10.7748/ns2012.11.27.10.49.c9400

Cited by 4 publications

(1 citation statement)

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“…Enuresis is resolved spontaneously as the children grow up. Its prevalence is 15% at the age of 5, 5% at the age of 10, and 1% at the age of 15 (11). It is defined as monosymptomatic enuresis if the child does not have voiding dysfunction and also daily incontinency (4,12).…”

Section: Introductionmentioning

confidence: 99%

Folic Acid and Vitamin B12 Deficiency, Two New Findings in Pediatric Enuresis

Kompani,

Barati,

Mehrjerdian

et al. 2023

Iran J Pediatr

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Background: Enuresis is one of the most common diseases in children. Although there are several factors involved in the occurrence of this diseases, the root cause of it has remained undetermined. Objectives: Identifying various factors responsible for enuresis may enormously contribute to solving this problem. This study, therefore, aimed to determine the level of vitamin B12 and folic acid in children with enuresis in Gorgan in 2021. Methods: In this case-control study, 43 children with primary enuresis and 99 children without enuresis, as the control group, referring to Taleghani Hospital in 2021 were included. Folic acid and vitamin B12 levels in two groups were measured and analyzed using statistical techniques. Results: Out of all participants, 23 (53.5%) in the case group and 53 (53.5%) in the control group were male. The mean age of children in the case and control groups were 7.60 ± 3.02 and 8.93 ± 3.15, respectively, and the two groups were not significantly different in terms of gender and age. Vitamin B12 and folic acid levels in the case group were significantly lower than those in the control group (P-value = 0.001). There was a significant difference between the case and control groups regarding the mean levels of vitamin B12 and folic acid levels based on sex and gender. Conclusions: In sum, it was found that children with enuresis suffered from deficiency of vitamin B12 and folic acid to some extent, which may have been a factor responsible for delaying the maturation of the central nervous system and, consequently, inducing enuresis in children.

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Section: Introductionmentioning

confidence: 99%

Folic Acid and Vitamin B12 Deficiency, Two New Findings in Pediatric Enuresis

Kompani,

Barati,

Mehrjerdian

et al. 2023

Iran J Pediatr

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Non-dipping phenomenon in children with monosymptomatic nocturnal enuresis

et al. 2013

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PurposeMonosymptomatic nocturnal enuresis is a common disorder seen in childhood, and many factors play a role in its etiopathology to varying degrees. The aim of our study was to investigate the possible association between nocturnal enuresis and 24-h blood pressure profiles of enuretic children.MethodsA total of 45 children ranging in age from 6 to 15 years with monosymptomatic nocturnal enuresis and 22 age-matched healthy controls were enrolled in our study. The blood pressure measurement was made at 30-min intervals during a 24-h period via an ambulatory blood pressure measurement device. Both groups underwent medical tests that included a complete blood count, blood biochemistry profile, urinalysis and blood renin–aldosterone levels, and all study subjects received an abdominal ultrasound.ResultsStatistically significant high nocturnal blood pressure levels were observed in our patients with monosymptomatic nocturnal enuresis compared with the control group (p < 0.05). The mean values of the day-to-night difference (dipping) in the systolic and diastolic blood pressure of the patients were significantly lower than those of control group (p < 0.05).ConclusionNocturnal enuresis should not only be accepted as a urinary system disorder. Possible systemic causative factors have to be examined, especially in patients that are resistant to first-line therapy. Based on the results of our study, we deduce that one of the factors that plays a role in the pathogenesis of enuresis nocturna is a non-dipping blood pressure profile (the “non-dipping” phenomenon).

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