Nocturnal Hemodialysis Restores Impaired Coronary Endothelial Function in End-Stage Renal Patients Receiving Conventional Hemodialysis

The Association Between Conversion to In-centre Nocturnal Hemodialysis and Left Ventricular Mass Regression in Patients With End-Stage Renal Disease

“…Les critères d' evaluation general 10,11 and dialysis 12 populations, the change in LVM has been the primary endpoint of randomized controlled trials evaluating intensified hemodialysis regimens. 7,13,14 Despite the potential benefits of dialysis intensification such as improvement in endothelial function, 15 many patients may have significant psychosocial, physical, or cognitive barriers that preclude home hemodialysis that is currently used by only 4% of the prevalent dialysis population in Canada. [16][17][18] In-centre nocturnal hemodialysis (INHD), delivered 3 times/ week and for 7-8 hours per session, presents a unique opportunity for dialysis intensification without the burdens of self-care.…”

An acute rise of plasma Na+concentration associates with syndecan-1 shedding during hemodialysis

“…Hemodialysis (HD) patients have extremely increased cardiovascular (CV) morbidity and mortality (39) and endothelial dysfunction (ED) is believed to have a major pathophysiological role (16,39,45,48). Several studies have shown that HD patients have impaired endothelial function (12,31) and markers of ED were found to predict survival of HD patients (43). Vlahu et al showed that dialysis patients had a loss of the endothelial glycocalyx (eGC) thickness compared with healthy controls (52).…”