Nocturnal Ventilation in Chronic Hypercapnic Respiratory Diseases

Pamidi, Sushmit.a.; Mokhlesi, Babak

doi:10.1016/b978-1-4377-1703-7.10020-9

Cited by 3 publications

(1 citation statement)

References 94 publications

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“…Under oxygen therapy, respiratory support is provided to hypoxemic patients where blood oxygen level is improved and maintained at least above 90% [62]. Non-invasive ventilation is an assisted respiratory support technique which is used to avoid the difficulties faced during intubation [64]. It is usually approved for patients at early stages of COVID-19 infection and also for individuals with milder immunosuppressive and cardiovascular complications but it only delays the invasive ventilation [65,61].…”

Section: Non-pharmacological Managementmentioning

confidence: 99%

Role of Nanotechnology in Diagnosing, Safeguarding, and Treating COVID-19

Rohini M. de Silvaa,

Kenneth Hulugallaa,

Panchali Ranasinghe

et al. 2023

SQU Journal for Science

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Coronavirus disease (COVID-19) is arguably the worst health crisis the world has faced in the 21st century, and the World Health Organization declared this a “public health emergency of international concern” during the beginning of the pandemic and continued for a significant period of time. Considering the public health risk and the delay in introducing a suitable medical intervention to eradicate this virus, many reserachers embarked on different technologies to develop a cure. Nanotechnology has emerged as a promising weapon in the fight against COVID-19 and other similar viral diseases. The unique qualities of nanomaterials make them excellent for a variety of applications, including the development of low-cost, real-time diagnostic systems, reusable personal protective equipment, and innovative carriers for biological cargo such as mRNA in vaccines and CRISPR/Cas9 in gene editing. In this review the current available pharmacological and non-pharmacological options that are being used around the world against COVID-19 are compared with their nanotechnological counterparts. Here, we also elaborate the advantages of currently available nanotechnology-based diagnostics, protective equipment, vaccines and therapeutics and discuss future directions and steps that should be taken to translate these technologies into a clinical setting to combat the COVID-19 pandemic.

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Section: Non-pharmacological Managementmentioning

confidence: 99%

Role of Nanotechnology in Diagnosing, Safeguarding, and Treating COVID-19

Rohini M. de Silvaa,

Kenneth Hulugallaa,

Panchali Ranasinghe

et al. 2023

SQU Journal for Science

View full text Add to dashboard Cite

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Investigating the effect of materials and structures for negative pressure ventilators suitable for pandemic situation

et al. 2021

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The onset of the corona virus disease 2019 (COVID-19) pandemic caused shortages in mechanical ventilators (MVs) essential for the intensive care unit (ICU) in the hospitals. The increasing crisis prompted the investigation of ventilators which is low cost and offers lower health complications. Many researchers are revisiting the use of negative pressure ventilators (NPVs), due to the cost and complications of positive pressure ventilators (PPVs). This paper summarizes the evolution of the MVs, highlighting the limitations of popular positive and negative pressure ventilators and how NPV can be a cost-effective and lower health complication solution. This paper also provides a detailed investigation of the structure and material for the patient enclosure that can be used for a cost-effective NPV system using ANSYS simulations. The simulation results can confirm the selection and also help in developing a low cost while based on readily available materials. This can help the manufacturer to develop low-cost NPV and reduce the pressure on the healthcare system for any pandemic situation similar to COVID-19.

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