Nodular prurigo: metabolic diseases are a common association

Winhoven, S. M.; Gawkrodger, D.J.

doi:10.1111/j.1365-2230.2006.02310.x

Cited by 28 publications

(22 citation statements)

References 4 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Systemic and metabolic causes have been implicated in 38% to up to 50% of PN cases [25,26]. Some common systemic associations of PN are chronic renal failure, liver disease (chronic hepatitis B, primary biliary cholangitis, chronic autoimmune cholestatic hepatitis), HIV, thyroid disease, diabetes and malignances, specifically non-Hodgkin's lymphoma [3,4,[27][28][29][30][31][32][33][34][35][36].…”

Section: Systemicmentioning

confidence: 99%

See 1 more Smart Citation

Diagnostic Workup and Evaluation of Patients with Prurigo Nodularis

et al. 2019

View full text Add to dashboard Cite

Prurigo nodularis (PN) is a chronic inflammatory skin disease characterized oftentimes by symmetrically distributed, severely pruritic nodules. Currently, the pathophysiology of PN remains to be fully elucidated, but emerging evidence suggests that neuroimmune alterations play principal roles in the pathogenesis of PN. There are several associated etiologic factors thought to be associated with PN, including dermatoses, systemic, infectious, psychiatric, and neurologic conditions. We conducted a systematic literature review to evaluate the clinical presentation, diagnosis, and etiologic factors of PN. In this review, we discuss common differential diagnoses of PN and recommend an evidence-based, standardized diagnostic evaluation for those with suspected PN.

show abstract

Section: Systemicmentioning

confidence: 99%

“…Rarer malignancies that have been associated with PN are metastatic transitional cell carcinoma of the bladder and Hodgkin's lymphoma [30,38,39]. Other less commonly associated systemic causes are gout, iron-deficiency anemia, and celiac disease [26,32,40,41].…”

Section: Systemicmentioning

confidence: 99%

Diagnostic Workup and Evaluation of Patients with Prurigo Nodularis

et al. 2019

View full text Add to dashboard Cite

show abstract

“…However, treating PN and interrupting the itch-scratch cycle remain difficult (9). PN has been reported to be associated with metabolic and endocrine disorders; 17% of PN patients have been found to have diabetes (16)(17)(18).…”

Section: Discussionmentioning

confidence: 99%

Successful Treatment of Chronic Intractable Itching Using Oral Pregabalin in a Patient with Diabetes and Systemic Prurigo Nodularis: A Case Report of an Iliopsoas Muscle Abscess

et al. 2013

View full text Add to dashboard Cite

A 73-year-old Japanese man developed chronic intractable itching due to prurigo nodularis. High-dose glucocorticoid ointment failed, and the treatment resulted in poor glycemic control. Repeated scratching caused hematogenous bacterial dissemination via cutaneous injuries, resulting in the formation of iliopsoas and spinal epidural abscesses that required long-term antibiotic treatment. Pregabalin was administered to treat the pruritus, and a considerable improvement was observed. A reduction in the dose and intensity of the topical corticosteroids improved the patient's glycemic control, resulting in the complete resolution of the abscesses. Pregabalin significantly improved the patient's pruritus and decreased the risk of infection.

show abstract

“…Les causes de ces prurits chroniques sont énumérées dans le tableau II [4][5][6][7][12][13][14][15]. Il faut garder en tête que des maladies graves, comme les lymphomes, peuvent être révélées par des prurits chroniques, chez l'adulte comme chez l'enfant.…”

Section: Prurigo Chronique Avec Lésions Cutanées Associéesunclassified