Nodular pulmonary amyloidosis with unusual, widespread lung cysts

Chew, Kian Ming; Clarke, Michael J.; Dubey, Niraj; Seet, Ju Ee

doi:10.11622/smedj.2013062

Cited by 23 publications

(17 citation statements)

References 13 publications

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“…Lung involvement in tracheobronchial papillomatosis may be in form of nodules that cavitate and form cysts [8]. In nodular forms of amyloidosis subpleural, lower lobe predominant cysts may be seen [9]. Recurrent pneumothorax, skin lesions and frequent urination…”

Section: Case Reportmentioning

confidence: 99%

Recurrent pneumothorax, skin lesions and frequent urination

Deokar

Chauhan

Dutt

et al. 2020

Breathe

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Section: Case Reportmentioning

confidence: 99%

Recurrent pneumothorax, skin lesions and frequent urination

Deokar

Chauhan

Dutt

et al. 2020

Breathe

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“…Localized pulmonary amyloidosis usually presents with pulmonary nodules, but in rare cases it may present with diffuse cystic changes. 110 Lung amyloidosis could be seen with Sjögren syndrome, which might be associated with mucosa-associated lymphoid tissue lymphoma in some cases. 111 Diagnosis of pulmonary amyloidosis requires histopathological examination by lung biopsy.…”

Section: Amyloidosismentioning

confidence: 99%

Diffuse Cystic Lung Diseases

et al. 2019

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Diffuse cystic lung diseases (DCLDs) are a group of diverse pulmonary disorders with varying pathophysiology that are characterized by the presence of thin-walled, air-filled spaces within lung parenchyma. High-resolution computed tomography plays a crucial role in the evaluation of DCLDs, and cyst characteristics such as morphology, distribution, and the presence of other associated radiologic findings can help distinguish between different DCLDs. DCLDs can be classified according to their underlying pathophysiology as neoplastic, genetic, lymphoproliferative, infectious, associated with other forms of interstitial lung disease, or related to smoking. In this review we will provide a clinical overview on the most common DCLDs that are encountered in clinical practice: lymphangioleiomyomatosis, pulmonary Langerhans cell histiocytosis, Birt-Hogg-Dubé syndrome, and lymphoid interstitial pneumonia/follicular bronchiolitis, with a focus on practical aspects that can help clinicians in the optimal diagnosis and management of patients with DCLDs.

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“…45 HRCT manifestations commonly include nodules, lymphadenopathy, and cysts. 46,33 Cyst formation is believed to correspond to dilation of the small airways. The cysts are thin walled, round and measure up to 2 cm in size.…”

Section: Lymphangioleiomyomatosis (Lam) (Figure 25)mentioning

confidence: 99%

Cystic Lung Diseases

Raoof

Bondalapati

Vydyula

et al. 2016

Chest

125

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Cysts are commonly seen on CT scans of the lungs, and diagnosis can be challenging. Clinical and radiographic features combined with a multidisciplinary approach may help differentiate among various disease entities, allowing correct diagnosis. It is important to distinguish cysts from cavities because they each have distinct etiologies and associated clinical disorders. Conditions such as emphysema, and cystic bronchiectasis may also mimic cystic disease. A simplified classification of cysts is proposed. Cysts can occur in greater profusion in the subpleural areas, when they typically represent paraseptal emphysema, bullae, or honeycombing. Cysts that are present in the lung parenchyma but away from subpleural areas may be present without any other abnormalities on high-resolution CT scans. These are further categorized into solitary or multifocal/diffuse cysts. Solitary cysts may be incidentally discovered and may be an age related phenomenon or may be a remnant of prior trauma or infection. Multifocal/diffuse cysts can occur with lymphoid interstitial pneumonia, Birt-Hogg-Dubé syndrome, tracheobronchial papillomatosis, or primary and metastatic cancers. Multifocal/diffuse cysts may be associated with nodules (lymphoid interstitial pneumonia, light-chain deposition disease, amyloidosis, and Langerhans cell histiocytosis) or with ground-glass opacities (Pneumocystis jirovecii pneumonia and desquamative interstitial pneumonia). Using the results of the high-resolution CT scans as a starting point, and incorporating the patient's clinical history, physical examination, and laboratory findings, is likely to narrow the differential diagnosis of cystic lesions considerably.

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Nodular pulmonary amyloidosis with unusual, widespread lung cysts

Cited by 23 publications

References 13 publications

Recurrent pneumothorax, skin lesions and frequent urination

Recurrent pneumothorax, skin lesions and frequent urination

Diffuse Cystic Lung Diseases

Cystic Lung Diseases

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