Nodular Sarcoid Myositis of Skeletal Muscle Diagnosed by Fine Needle Aspiration Biopsy

Histoplasmosis as a Cause of Nodular Myositis in an AIDS Patient Diagnosed on Fine Needle Aspiration Cytology

“…Localized nodular myositis, 6 a variant of polymyositis, a syndrome of acutely developing, painful, focal inflammatory nodules was ruled out, as there was no clinical evidence of collagen vascular disease. Nodular sarcoid myositis presents as painful, growing nodules in the muscles of the extremities and is demonstrated as starshaped areas of low signal intensity surrounded by areas of high signal intensity on T2-weighted magnetic resonance imaging 7 ; that was not the picture in our case.…”

Aspiration biopsy of nodular sarcoidosis of the muscle

“…4 To our knowledge, there has been only one report of a nodular form of muscular sarcoidosis that was diagnosed using FNAB. Guo et al 3 in 1999 described a 31-yr-old female patient with a nodular form of sarcoidosis in the calf that was diagnosed using FNAB. The patient was diagnosed as having sarcoidosis before she sought medical treatment for the calf mass.…”

“…When evaluating smears of patients with a suspicion of muscular sarcoidosis, Guo et al 3 cautioned that degener- ated, multinucleated muscle cells should not be confused with Langhans-type giant cells. Cytoplasm in the multinucleated muscle cells might lack striation due to degeneration.…”

“…Cytoplasm in the multinucleated muscle cells might lack striation due to degeneration. Guo et al 3 recommended an immunohistochemical technique to distinguish muscle cells from Langhans-type giant cells using CD68 and muscle-specific actin.…”

“…To our knowledge, there has been only one previous report describing aspiration cytology findings of nodular muscular sarcoidosis in the English-language literature. 3 …”