2013 22nd International Conference on Noise and Fluctuations (ICNF) 2013
DOI: 10.1109/icnf.2013.6578905
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Noise analysis and measurement of integrator-based sensor interface circuits for fluorescence detection in lab-on-a-chip applications

Abstract: Lab-on-a-chip (LOC) biological assays have the potential to fundamentally reform healthcare. The move away from centralized facilities to Point-of-Care (POC) testing of biological assays would improve the speed and accuracy of these, thereby improving patient care. Before LOC can be realized, a number of challenges must be addressed: the need for expert users must be abstracted away; the manufacturing cost of $5 per test threshold must be met; and the supporting infrastructure must be integrated down to an eas… Show more

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Cited by 4 publications
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“…Figure 5D presents estimates of acceptable noise levels for various on/off ratios on the devices β and integration times t meas . This noise level corresponds to the input referred noise of the op-amp calculated using standard noise analysis in integrator-based circuits (Jensen et al, 2013 ). If t meas is taken as 20 ns following the quantization error consideration discussed above, the acceptable noise levels are relatively low of the order of just 5 as seen in Figure 5D curve 1.…”
Section: Resultsmentioning
confidence: 99%
“…Figure 5D presents estimates of acceptable noise levels for various on/off ratios on the devices β and integration times t meas . This noise level corresponds to the input referred noise of the op-amp calculated using standard noise analysis in integrator-based circuits (Jensen et al, 2013 ). If t meas is taken as 20 ns following the quantization error consideration discussed above, the acceptable noise levels are relatively low of the order of just 5 as seen in Figure 5D curve 1.…”
Section: Resultsmentioning
confidence: 99%