Noise Exposure Effects on Blood Glucose, Cortisol and Weight Changes in the Male Mice

Abstract

Background: Noise is one of the most important hazardous factors in industrial environments. Noise has many important negative effects on health; it can cause damage auditory, visual, neurological and psychological and hormonal systems, and physiological and cognitive functions. Objectives: The current study aimed to investigate the effects of noise exposure on changes in glucose and cortisol serum levels in adult male mice. Methods: A total of 24 adult male mice were randomly divided into two experimental and one control groups. One of the experimental groups was exposed to a noise pressure level of 90 dB played by Cool Edit software on a computer in a frequency range 700 -5700 Hz, and the other one was exposed to the same noise and received an injection of streptozotocin (60 mg/kg). The experimental groups were exposed to the noise for 30 days, eight hours per day. Twenty-four hours after the end of the exposure period the fasting cortisol and glucose serum levels were measured in the mice of the three groups. Results:The study results showed a significant difference in the level of glucose in non-diabetic and diabetic groups exposed to the noise, compared to the control subjects (P < 0.002). In addition, there was a significant difference in the level of cortisol in non-diabetic and diabetic groups exposed to the noise, compared to the control groups (P < 0.002). Conclusions:The results showed that exposure to a 90 dB noise can increase cortisol and glucose levels. Hence, in work environments where people are exposed to noise, it is expected that such noises have a negative impact on them and the noise may increase cortisol and blood sugar levels.

Assortment of kaempferol and zinc gluconate improves noise-induced biochemical imbalance and deficits in body weight gain

“…Results from this study showed that the body weight gain of male rats was significantly decreased in the group exposed to noise without antioxidant treatment, indicating that noise exerts a negative effect on the growth and development of rats. This corroborates previously reported studies (Jalali et al, 2012;Taban, Mortazavi, Vosoughi, Khavanin, & Asilian Mahabadi, 2017) which affirm the inhibitory effect of noise on body weight gain in exposed subjects. Our results demonstrate that coadministration of kaempferol and zinc gluconate significantly improved noise-induced deficit in body weight gain observed in the exposed rats.…”

Chronic noise-exposure exacerbates insulin resistance and promotes the manifestations of the type 2 diabetes in a high-fat diet mouse model

“…Similarly, Cui et al reported that chronic noise exposure induced a persistent increase in blood corticosterone level as well as glucose dysregulation in rats[ 5 ]. More recently, another experimental study also reported increases of glucose and cortisol serum levels in mice after 30 days noise exposure [ 34 ]. These separate studies provided consistent evidence pointing to the possibility that the stress effect is (at least a part of) the rationale behind the diabetogenic effects of noise.…”

Evaluating the Effects of Noise Pollution on the Levels of Blood Cortisol, Testosterone, and Thyroid in Male Wistar Rats

“…The studies conducted by Farzadinia et al (26) and Smitha and Mukkadan (31) showed that noise increased cortisol levels in rats, which is consistent with the results of the current study. The results of Taban et al also showed that exposure to noise higher than 90 dB causes increased glucose and cortisol in male rats (32). Although we cannot directly compare the results of laboratory animal studies with human studies, it is important to note that cortisol is commonly recognized as a stress hormone.…”