Noise-induced hearing loss

Ivory, Robert; Kane, Rebecca; Diaz, Rodney C.

doi:10.1097/moo.0000000000000085

Cited by 31 publications

(13 citation statements)

References 21 publications

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“…It has been reported that despite an apparent understanding of the effects of noise exposure from loud activities, much of the public appears unconcerned about the use of HPDs during recreational activities ( 9 ). As part of a health belief model, a construct to describe factors that affect participation in a health behavior and personal experience of noise injury symptoms, as well as awareness of the benefits of ear plugs and the long-term implications of hearing damage are key motivators for using HPDs ( 10 ).…”

Section: Discussionmentioning

confidence: 99%

Use of Personal Hearing Protection Devices at Loud Athletic or Entertainment Events Among Adults — United States, 2018

Eichwald¹,

Scinicariello²,

Telfer³

et al. 2018

MMWR Morb. Mortal. Wkly. Rep.

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Section: Discussionmentioning

confidence: 99%

Use of Personal Hearing Protection Devices at Loud Athletic or Entertainment Events Among Adults — United States, 2018

Eichwald¹,

Scinicariello²,

Telfer³

et al. 2018

MMWR Morb. Mortal. Wkly. Rep.

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“…For our exploratory study of the potential effects and underlying mechanisms of noise exposure on glucose homeostasis, we exposed mice to 95-dB SPL noise for 4 hr per day, consistent with the regulatory limit for industrial noise exposure in the United States (OSHA 1983). However, noise exposure at or beyond this level may also occur in nonoccupational settings, such as at sporting events, loud concerts, and motorized sporting facilities, where peak sound levels of 110–117 A-weighted decibels (dBA) (equivalent to continuous exposure at 85–97 dBA) have been reported (Cranston et al 2013; Ivory et al 2014). The present data indicated that although noise exposure did not cause significant hearing loss (as indicated by comparable ABR thresholds in the control and noise-exposed groups), it did cause temporary insulin resistance that was prolonged with longer noise exposure and was consistent with the evidence of blunted insulin signaling in skeletal muscle.…”

Section: Discussionmentioning

confidence: 99%

Effects of Noise Exposure on Systemic and Tissue-Level Markers of Glucose Homeostasis and Insulin Resistance in Male Mice

Liu

Wang

et al. 2016

Environ Health Perspect

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Background:Epidemiological studies have indicated that noise exposure is associated with an increased risk of type 2 diabetes mellitus (T2DM). However, the nature of the connection between noise exposure and T2DM remains to be explored.Objectives:We explored whether and how noise exposure affects glucose homeostasis in mice as the initial step toward T2DM development.Methods:Male ICR mice were randomly assigned to one of four groups: the control group and three noise groups (N20D, N10D, and N1D), in which the animals were exposed to white noise at 95 decibel sound pressure level (dB SPL) for 4 hr per day for 20 successive days, 10 successive days, or 1 day, respectively. Glucose tolerance and insulin sensitivity were evaluated 1 day, 1 week, and 1 month after the final noise exposure (1DPN, 1WPN, and 1MPN). Standard immunoblots, immunohistochemical methods, and enzyme-linked immunosorbent assays (ELISA) were performed to assess insulin signaling in skeletal muscle, the morphology of β cells, and plasma corticosterone levels.Results:Noise exposure for 1 day caused transient glucose intolerance and insulin resistance, whereas noise exposure for 10 and 20 days had no effect on glucose tolerance but did cause prolonged insulin resistance and an increased insulin response to glucose challenge. Akt phosphorylation and GLUT4 translocation in response to exogenous insulin were decreased in the skeletal muscle of noise-exposed animals.Conclusions:Noise exposure at 95 dB SPL caused insulin resistance in male ICR mice, which was prolonged with longer noise exposure and was likely related to the observed blunted insulin signaling in skeletal muscle.Citation:Liu L, Wang F, Lu H, Cao S, Du Z, Wang Y, Feng X, Gao Y, Zha M, Guo M, Sun Z, Wang J. 2016. Effects of noise exposure on systemic and tissue-level markers of glucose homeostasis and insulin resistance in male mice. Environ Health Perspect 124:1390–1398; http://dx.doi.org/10.1289/EHP162

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“…The clinical implications of NIHHL are manifested by the fact that noise exposure causing NIHHL occurs frequently in daily life and impacts much more general population [ 90 ]. Such noise exposure has been generally considered to be safe according to current safety standards for exposure to noise.…”

Section: Clinical Implications and Future Directionsmentioning

confidence: 99%

Cochlear Synaptopathy and Noise-Induced Hidden Hearing Loss

Shi

Chang

et al. 2016

Neural Plasticity

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Recent studies on animal models have shown that noise exposure that does not lead to permanent threshold shift (PTS) can cause considerable damage around the synapses between inner hair cells (IHCs) and type-I afferent auditory nerve fibers (ANFs). Disruption of these synapses not only disables the innervated ANFs but also results in the slow degeneration of spiral ganglion neurons if the synapses are not reestablished. Such a loss of ANFs should result in signal coding deficits, which are exacerbated by the bias of the damage toward synapses connecting low-spontaneous-rate (SR) ANFs, which are known to be vital for signal coding in noisy background. As there is no PTS, these functional deficits cannot be detected using routine audiological evaluations and may be unknown to subjects who have them. Such functional deficits in hearing without changes in sensitivity are generally called “noise-induced hidden hearing loss (NIHHL).” Here, we provide a brief review to address several critical issues related to NIHHL: (1) the mechanism of noise induced synaptic damage, (2) reversibility of the synaptic damage, (3) the functional deficits as the nature of NIHHL in animal studies, (4) evidence of NIHHL in human subjects, and (5) peripheral and central contribution of NIHHL.

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Noise-induced hearing loss

Cited by 31 publications

References 21 publications

Use of Personal Hearing Protection Devices at Loud Athletic or Entertainment Events Among Adults — United States, 2018

Use of Personal Hearing Protection Devices at Loud Athletic or Entertainment Events Among Adults — United States, 2018

Effects of Noise Exposure on Systemic and Tissue-Level Markers of Glucose Homeostasis and Insulin Resistance in Male Mice

Cochlear Synaptopathy and Noise-Induced Hidden Hearing Loss

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