Nomenclature for factors of the HLA system, update April, May and June 2022

Marsh, Steven G.E.

doi:10.1111/tan.14739

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Hla Allele Cell Identification Accession Number Submitting A...2

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Cited by 9 publications

(8 citation statements)

References 62 publications

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“…The following sequences have been submitted to the Nomenclature Committee since the April, May and June 2023 nomenclature update 1 and, following agreed policy, have been assigned official allele designations 2 . Full details of all sequences will be published in a forthcoming report.…”

Section: Hla Allele Cell Identification Accession Number Submitting A...mentioning

confidence: 99%

Nomenclature for factors of the HLA system, update July, August and September 2023

Marsh

2023

HLA

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Section: Hla Allele Cell Identification Accession Number Submitting A...mentioning

confidence: 99%

Nomenclature for factors of the HLA system, update July, August and September 2023

Marsh

2023

HLA

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“…The following sequences have been submitted to the Nomenclature Committee since the April, May and June 2023 nomenclature update (Marsh et al., 2023) and, following agreed policy, have been assigned official allele designations (Marsh et al., 2010). Full details of all sequences will be published in a forthcoming report.…”

Section: Hla Allele Cell Identification Accession Number Submitting A...mentioning

confidence: 99%

Nomenclature for factors of the HLA system, update July, August and September 2023

Marsh

2023

Int J Immunogenetics

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“…The objective of this study was to determine the molecular and functional characteristics of a novel null HLA‐A allele, HLA‐A*24:608N (accession number LC715480) 4 which was recently identified in five Korean individuals. The novel allele had approximately 12 k base pairs deletion from intron 3 to 3′ end of the HLA‐A gene.…”

Section: Introductionmentioning

confidence: 99%

Characterization of novel HLA‐A24:608N* allele discovered in Koreans

Jeong,

Lee,

Kwon

et al. 2023

HLA

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A novel null HLA‐A*24 allele, HLA‐A*24:608N, was identified in five Korean subjects including three from a family and two separate individuals. This study was performed to discern its immunological function in transplantation settings. Because this null variant had deletions of approximately 12 k base pairs from intron 3 to 3′ end of the HLA‐A gene, low resolution HLA typing and amplicon‐based next generation sequencing (NGS) typing methods had failed to assign it. Hybrid capture‐based NGS method confirmed that this novel variant had a large deletion. T‐lymphocyte crossmatching by complement‐dependent lymphocytotoxicity and flow cytometry with a serum consisting anti‐HLA‐A24 antibody revealed negative results, implying that an individual with this allele would not carry a functioning A24 antigen. These findings highlight the importance of identifying a null HLA allele by employing appropriate molecular method and providing expected crossmatching outcomes in a real‐world transplantation setting.

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Nomenclature for factors of the HLA system, update April, May and June 2022

Cited by 9 publications

References 62 publications

Nomenclature for factors of the HLA system, update July, August and September 2023

Nomenclature for factors of the HLA system, update July, August and September 2023

Nomenclature for factors of the HLA system, update July, August and September 2023

Characterization of novel HLA‐A24:608N* allele discovered in Koreans

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Nomenclature for factors of the HLA system, update April, May and June 2022

Cited by 9 publications

References 62 publications

Nomenclature for factors of the HLA system, update July, August and September 2023

Nomenclature for factors of the HLA system, update July, August and September 2023

Nomenclature for factors of the HLA system, update July, August and September 2023

Characterization of novel HLA‐A*24:608N allele discovered in Koreans

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Product

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Characterization of novel HLA‐A24:608N* allele discovered in Koreans