We consider the description of second-class constraints in a Lagrangian path integral associated with a higher-order ∆-operator. Based on two conjugate higher-order ∆-operators, we also propose a Lagrangian path integral with Sp(2) symmetry, and describe the corresponding system in the presence of second-class constraints.NBI-HE-96-60 UUITP-09/97 hep-th/9703199 * Here, and in the following, [·, ·] equals the graded supercommutator: [A, B] = AB − (−1) ǫ A ǫ B BA.