Non- adherence to anti-retroviral medication in Shiraz, 2014: a cross sectional study

Abstract

BackgroundMedication adherence is a dynamic and complex behavioral process, which is strongly influenced by personal, social and environmental factors.ObjectivesTo determine the prevalence and factors affecting non-adherence to medication among HIV-infected patients.Methods and materialsDesignA cross-sectional study.SettingVoluntary Counseling and Testing Center (VCT), Shiraz, Fars province, in the South of Iran.PatientsAmong HIV-positive patients who received anti-retroviral therapy, 214 adult patients were selected through convenience sampling. Their medication adherence was checked by interview and counting the pills on visits during two months. Clinical and laboratory data were obtained from the patients' records.ResultsNon-adherence and adherence groups included 30.4% (65) and 69.6% (149) of the patients, respectively. The mean age of patients was 40.80±7.77 years, and ranged from 20 to 65 years. Majority of cases (65%) were male. A significant relationship was found between non-adherence to medications and the variables of transmission method, marital status, housing status, and CD4, but there was no significant relationship with gender.ConclusionThe prevalence of medication adherence was similar to other regions with limited financial resources. To increase patient's medication adherence, they should be exposed to motivational interventions to promote their drug consumption, social and occupational support.

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“…However, cross-sectional study conducted in Shiraz showed that prevalence of nonadherence was 30.4%. 19 This small difference between our study and that of study conducted in Shiraz may be due to the fact that studies were done in different sociocultural areas. More over the difference could be due to differences in design of the studies that is in our study we used pre-post intervention study but the other study is cross sectional.…”

“…3 Study in Brazil found that nonadherence to ART among patients initiating the therapy was 36.9% in 2005. 4 A study conducted in Northwest Ethiopia indicated that nonadherence to ART among adult hospitalized patients was 19.1% in 2014. 5 Nonadherence to ART is related to different factors.…”

<p>Antiretroviral Treatment Adherence and Determinant Factors Among Adult People Infected with Human Immunodeficiency Virus in Eastern Tigray General Hospitals, Northern Ethiopia, 2019</p>

“…The study is higher than studies done in Northern Ethiopia (62.3%), 24 Southern Ethiopia (60%,56%), 25,26 Eastern Ethiopia (65%), 27 Western Africa (62.6%), 28 Southern-central Africa (63.81%), 29 Southern Africa (70.8%), 30 and Western Asia (69.6%). 31 This variation might be due to differences in adherence measurement, and socio-demographic characteristics. In this study, relationships were found between ART adherence and different variables.…”

Sexuality and other issues in Africa and beyond

“…HIV of course is the big story here, with authors reporting adherence to ART23, physical activity24 and disputes over HIV diagnosis by ELISA25, hepatitis C26 and surveillance of epidemic prone diseases 27…”