“…Various studies conducted in Western populations revealed factors associated with nonadherence that were similar to that elicited in our traditional multivariable analyses, specifically with regard to higher triglyceride levels and less severe DR. 8 , 12 , 17 Considering that DR has few visual symptoms until the disease becomes quite advanced, 18 it is not unusual for patients with mild disease to not realize the importance of early intervention, which likely explains our observation of the association between milder disease with higher rates of nonadherence rates to PSOR. In contrast, despite an established correlation between poor disease control and lack of adherence to various disease intervention strategies, 19 it is surprising that only higher triglyceride levels, and not other indicators of poor control, for example, raised HbA1c and blood pressure levels, were significantly associated with increased risk of nonadherence to PSOR in our study.…”