Non-arteritic anterior ischemic optic neuropathy: role of systemic corticosteroid therapy

Abstract

This study suggested that NA-AION eyes treated during the acute phase with systemic corticosteroids resulted in a significantly higher probability of improvement in visual acuity (p = 0.001) and visual field (p = 0.005) than in the untreated group. Both visual acuity and visual fields improved up to 6 months after onset of NA-AION.

Bilateral Anterior Ischaemic Optic Neuropathy in a Child on Continuous Peritoneal Dialysis: Case report and literature review

“…The use of steroids is controversial, with some studies showing a positive outcome. 3,22,23 The use of combined levodopa and carbidopa has been found to improve visual acuity in patients with AION. 24 In addition, significant improvement in vision has been reported with steroids and levodopa.…”

Non-arteritic anterior ischemic optic neuropathy (NA-AION) after intravitreal injection of bevacizumab (Avastin®) for treatment of angoid streaks in pseudoxanthoma elasticum

“…At the time of NA-AION onset in this patient, no effective therapy for NA-AION was available [9,10]. Meanwhile, promising data on the beneficial effect of systemic corticosteroids on visual acuity and visual field improvement in the treatment of NA-AION have been published, and represent the only proven beneficial therapy option [11,12].…”

“…At the time of diagnosis of NA-AION in this patient and start of treatment with brimonidine (Alphagan®) no treatment for NA-AION had been proven beneficial. Reports about beneficial effect of systemically administered corticosteroids were not yet available [12].…”

Non-Arteritic Anterior Ischemic Optic Neuropathy (NAION)—A Brief Review

“…Few studies [25] [26] in literature concluded role of oral steroids in improvement of visual acuity and fields but results were not accepted due to non-randomization, small sample size, selection bias. No studies have documented role of intravenous steroids.…”