Non Calcaemic & Non Osteogenic Functions of Vitamin D: A Brief Review

Abstract

Vitamin D insufficiency affects almost 50% of the population worldwide. This can mainly be attributed to lifestyle (for example, reduced outdoor activities, liberal use of sunscreen) and environmental (for example, air pollution) factors that reduce exposure to sunlight, which is vital for ultraviolet-B (UVB)-induced vitamin D production. Vitamin D deficiency is common in all age groups. High prevalence of vitamin D insufficiency is a particularly important public health issue as Hypovitaminosis-D is an independent risk factor for several non communicable & communicable diseases. Current studies suggest that we may need more vitamin D than presently recommended to prevent chronic disease like Diabetes & Hypertension. Present review focuses on the non-calcemic and non-osteogenic role of Vitamin D and how Vitamin D deficiency might be an important risk factor in increased disease incidence & prevalence.

Long-Term Effects of Antiseizure Medications

“…An increased rate of cardiovascular events, some cancers including Hodgkin lymphoma, breast and colorectal cancer, depression and Alzheimer's disease have all been linked by association with Vitamin D deficiency. 34,35 Accepted Manuscript This article is protected by copyright. All rights reserved.…”

“…An increased rate of cardiovascular events, some cancers including Hodgkin's lymphoma, breast and colorectal cancer, depression, and Alzheimer's disease have all been linked by association with vitamin D deficiency. 34,35 Vitamin D deficiency is a common condition in persons with epilepsy. This is due to several reasons, including decreased exposure to sunlight in patients who are immobile, dietary reasons, and, importantly, to the long-term effects of their ASMs.…”