2024
DOI: 10.32604/biocell.2024.049160
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Non-coding RNA as future target for diagnose and treatment of perineural invasion in cancers

BINGJIE LI,
WENBO CAO,
JINJING XIAO
et al.

Abstract: Perineural invasion (PNI), a particularly insidious form of tumor metastasis distinct from hematogenous or lymphatic spread, has the capacity to extend well beyond the primary tumor site, infiltrating distant regions devoid of lymphatic or vascular structures. PNI often heralds a decrease in patient survival rates and is recognized as an indicator of an unfavorable prognosis across a variety of cancers. Despite its clinical significance, the underlying molecular mechanisms of PNI remain elusive, complicating t… Show more

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