Non-communicable disease co-morbidity and associated factors in tuberculosis patients: A cross-sectional study in Gabon

Adégbitè, Bayodé Roméo; Edoa, J. R.; Abdul, JBP Agbo Achimi; Epola, Micheska; Mevyann, Chester; Dejon-Agobé, JC; Zinsou, JF; Honkpéhèdji, Yabo Josiane; Mpagama, SG; Alabi, Aderemi Babatunde; Kremsner, P. G.; Klipstein‐Grobusch, Kerstin; Adegnika, A. A.; Grobusch, Martin P.

doi:10.1016/j.eclinm.2022.101316

Cited by 11 publications

(3 citation statements)

References 42 publications

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“…Although NCD multimorbidity among patients with TB is well known, relevant empirical studies have been conducted only in low-and middle-income countries with a high incidence of TB and mortality rates [5,[20][21][22][23]. As part of such efforts, the present study examined comorbidities at the time of TB onset in individuals in Korea.…”

Section: Introductionmentioning

confidence: 99%

Gender differences in tuberculosis patients with comorbidity: A cross-sectional study using national surveillance data and national health insurance claims data in South Korea

Moon

Jeong²,

Kang³

et al. 2023

PLoS ONE

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The coexistence of tuberculosis and other chronic diseases complicates disease management. Particularly, the lack of information on the difference in the prevalence of chronic diseases in tuberculosis based on age and gender can hinder the establishment of appropriate public health strategies. This study aimed to identify age- and gender-based differences in the prevalence of chronic diseases as comorbidities in patients with tuberculosis. An anonymized data source was established by linking the national health insurance claims data to the Korean national tuberculosis surveillance data from 2014 to 2018. The prevalence of chronic diseases was stratified by gender and age (age groups: ≤64, 65–74, and ≥75 years), and the differences in the prevalence of chronic diseases were analyzed by multinomial logistic regression and classified using the Charlson Comorbidity Index. A total of 148,055 patients with tuberculosis (61,199 women and 86,856 men) were included in this study. Among the patients aged ≥65 years, 48.2% were female and 38.1% were male. In this age group, the probability of chronic disease comorbidity was higher in female patients than in male patients. The prevalence of congestive heart failure and dementia as comorbidities in patients with tuberculosis increased more drastically with age in women than in men. Thus, the present study confirmed gender and age differences in the distribution of comorbidities among patients with tuberculosis. A more comprehensive gender-responsive approach for patients with tuberculosis and chronic diseases is required to alleviate the double burden of infectious diseases and non-communicable diseases in an aging society.

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Section: Introductionmentioning

confidence: 99%

Gender differences in tuberculosis patients with comorbidity: A cross-sectional study using national surveillance data and national health insurance claims data in South Korea

Moon

Jeong²,

Kang³

et al. 2023

PLoS ONE

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“…Considered a developing country in Central Africa, economic imbalances are widespread, the literacy rate is borderline average and basic health services are not only under-equipped but sometimes scarce. In Gabon, according to the World Health Atlas, the incidence of tuberculosis was estimated at 521/100,000 in 2019 [10]. According to the National Tuberculosis Control Programme (PNLT), the WHO ranks Gabon 4 th among African countries and territories for the incidence of tuberculosis, and with a high morbidity rate [11].…”

Section: Introductionmentioning

confidence: 99%

“…The mortality rate for people infected with both TB and HIV was 25% [13]. Faced with this situation, since 4 May 2021, at a workshop to validate its national strategic plan 2021-2025, the Gabonese government has made the fight against tuberculosis one of the priorities of the country's health sector development programme [10]. However, a review of the literature indicates that there is a paucity of studies on the prevalence of TB in patients in south-eastern Gabon.…”

Section: Introductionmentioning

confidence: 99%

Prevalence of Pulmonary Tuberculosis and Associated Factors among Patients Admitted to the Amissa Bongo University Hospital Center in Franceville, Gabon

Mba,

Obiang,

Kenguele

et al. 2023

JBM

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Background: In Gabon, the epidemiology of tuberculosis has been considerably reshaped by the AIDS virus. It is in this context that the present study was conducted to assess the prevalence of pulmonary tuberculosis and associated factors among patients at the Amissa Bongo Regional Hospital in Franceville, Gabon. Patients and Methods: This prospective, cross-sectional study was conducted in the biomedical analysis laboratory of the Amissa Bongo Regional University Hospital in Franceville from 19 June 2021 to 22 January 2022. After agreeing to take part in the study, participants were asked to fill in a questionnaire to collect their socio-demographic data and habits. Clinical signs were also observed. Sputum and gastric fluid samples were collected and examined using the Xpert MTB/RIF test and BAAR smear microscopy. Data were analysed using R software version 3.6.1. The results of the univariate and multivariate analyses were considered significant for p ≤ 0.05. Results: A total of 309 patients were included in this study, 50.81% (n = 157) men and 49.19% (n = 152) women. Of these, 98 had a positive diagnosis of pulmonary tuberculosis, giving an overall prevalence rate of 31.72%. There were 40 women or 40.82% (95% CI: [0.30 -0.51]) and 58 men or 59.18% (95% CI: [0.48 -0.69]). A univariate analysis of the prevalence of tuberculosis according to risk factors and clinical signs indicated a certain association between certain variables. However, an in-depth multivariate logistic regression

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Clinical epidemiology, genetic diversity, and drug susceptibility patterns by whole genome sequencing of Mycobacterium tuberculosis complex isolates in Gabon from 2012 to 2022

Adegbite,

Dreyer,

Agbo

et al. 2025

IJID Regions

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Non-communicable disease co-morbidity and associated factors in tuberculosis patients: A cross-sectional study in Gabon

Cited by 11 publications

References 42 publications

Gender differences in tuberculosis patients with comorbidity: A cross-sectional study using national surveillance data and national health insurance claims data in South Korea

Gender differences in tuberculosis patients with comorbidity: A cross-sectional study using national surveillance data and national health insurance claims data in South Korea

Prevalence of Pulmonary Tuberculosis and Associated Factors among Patients Admitted to the Amissa Bongo University Hospital Center in Franceville, Gabon

Clinical epidemiology, genetic diversity, and drug susceptibility patterns by whole genome sequencing of Mycobacterium tuberculosis complex isolates in Gabon from 2012 to 2022

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