Background
The global burden of cardiovascular mortality is increasing, as is
the number of large-scale humanitarian emergencies. The interaction between
these phenomena is not well understood. This review aims to clarify the
relationship between humanitarian emergencies and cardiovascular morbidity
and mortality.
Methods
With assistance from a research librarian, electronic databases
(PubMed, Scopus, CINAHL, Global Health) were searched in January 2014.
Findings were supplemented by reviewing citations of included trials.
Observational studies reporting the effect of natural disasters and conflict
events on cardiovascular morbidity and mortality in adults since 1997 were
included. Studies without a comparison group were not included. Double-data
extraction was utilized to abstract information on acute coronary syndrome
(ACS), acute decompensated heart failure (ADHF), and cardiac death (SCD).
Review Manager 5.0 was used to create figures for qualitative synthesis
(Version 5.2, Copenhagen Denmark, The Nordic Cochrane Centre).
Results
The search retrieved 1697 unique records; 24 studies were included
(17 studies of natural disasters, 7 studies of conflict). These studies
involved 14,583 cardiac events. All studies utilized retrospective designs:
4 were population-based, 15 were single-center, and 5 were multicenter
studies. 23 studies utilized historical controls in the primary analysis,
and 1 utilized primarily geographical controls. Conflicts are associated
with an increase in long-term morbidity from ACS; the short-term effects of
conflict vary by study. Natural disasters exhibit heterogeneous effects
including increased occurrence of ACS, ADHF, and SCD.
Conclusions
In certain settings, humanitarian emergencies are associated with
increased cardiac morbidity and mortality that may persist for years
following the event. Humanitarian aid organizations should consider
morbidity from non-communicable disease when planning relief and
recuperation projects.