Non-contraceptive Effects of Subdermal Levonogestrel Implant on Endometriosis Patient : A Case Report

Pasidri, Yogi

doi:10.34297/ajbsr.2021.11.001659

Cited by 1 publication

(2 citation statements)

References 4 publications

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“…In cases when pain continues to persist after medication intervention, surgical interventions may be considered, such as lesion excision or ablation, as well as adhesion lysis. The citations are (Gunardi et al, 2021;Supriyadi et al, 2017).…”

Section: Therapeutic Approach For Endometriosis and Its Side Effectmentioning

confidence: 99%

“…Prolonged hypoestrogenic and hypergestagenic circumstances may lead to the conversion of eutopic and ectopic endometrium into decidual structures. The occurrence of excessive bleeding as a side effect might be attributed to the low blood estradiol levels that are a consequence of ongoing progestin medication (Gezer & Oral, 2015;Gunardi et al, 2021). Individuals who utilize progestin hormones and subsequently develop bleeding issues are recognized to exhibit elevated amounts of lipid peroxides, particularly malondialdehyde (MDA).…”

Section: Therapeutic Approach For Endometriosis and Its Side Effectmentioning

confidence: 99%

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Potential Role of Propolis Flavonoid on Malondialdehyde and Superoxide Dismutase Levels on Endometriosis

Mayasari,

Retno Gunarti,

Octovia

2024

JLMH

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Endometriosis is a prevalent gynecological condition that affects around 10% of women within the reproductive age group globally. Recent research indicates that oxidative stress plays a significant role in the development of endometriosis. The present administration of progestin hormone treatment has been shown to induce additional oxidative stress, which is characterized by elevated levels of oxidative stress indicators, including malondialdehyde (MDA), and a reduction in the enzymatic antioxidant superoxide dismutase (SOD). The presence of hormonal imbalances in conjunction with these alterations fosters an environment conducive to the metastasis of endometrial cells. This process initiates inflammatory pathways, angiogenesis, and the formation of lesions and tumors, ultimately exacerbating the state of endometriosis. Research findings indicate that propolis has inherent antioxidant properties, characterized by a high concentration of flavonoid components and phenolic acids. Propolis contains active compounds that have the ability to trap free radicals by forming more stable molecules. Propolis has anti-inflammatory, antimicrobial, and immunomodulatory characteristics, hence potentially enhancing the patient's oxidative stress state, mitigating morbidity, and reducing the duration of hospitalization. This research aims to assess the possible impact of flavonoids found in propolis on the treatment of endometriosis.

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Section: Therapeutic Approach For Endometriosis and Its Side Effectmentioning

confidence: 99%

Section: Therapeutic Approach For Endometriosis and Its Side Effectmentioning

confidence: 99%

Potential Role of Propolis Flavonoid on Malondialdehyde and Superoxide Dismutase Levels on Endometriosis

Mayasari,

Retno Gunarti,

Octovia

2024

JLMH

View full text Add to dashboard Cite

show abstract

Non-contraceptive Effects of Subdermal Levonogestrel Implant on Endometriosis Patient : A Case Report

Abstract: This work is licensed under Creative Commons Attribution 4.0 License AJBSR.MS.ID.001659.

Cited by 1 publication

References 4 publications

Potential Role of Propolis Flavonoid on Malondialdehyde and Superoxide Dismutase Levels on Endometriosis

Potential Role of Propolis Flavonoid on Malondialdehyde and Superoxide Dismutase Levels on Endometriosis

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