In order to solve channel estimation's pilot interference problem, this paper researched OFDM system channel estimation model, analyzed the OFDM symbol's pilot pattern, proposed a new octagon guide frequency pattern design method, and combined with low signal to noise space of virtual pilot technology, used the interpolation method to eliminate interference, further improved the OFDM system channel estimation accuracy. Mathematical theory analysis carried out comparative experiments on different kinds of pilot pattern design methods, simulation results show that the octagon of pilot pattern was an optimal pilot pattern, this pilot shape reduced approximately 10% sample space better than similar methods, and provided better BER performance.