Non-enhanced MRI in combination with color Doppler flow imaging for improving diagnostic accuracy of parotid gland lesions

Zhang, Wei; Zuo, Zhichao; Luo, Ningbin; Liu, Lianfeng; Jin, Guanqiao; Liu, Junjie; Su, Danke

doi:10.1007/s00405-018-4895-6

Cited by 14 publications

(14 citation statements)

References 28 publications

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“…Our previous studies confirmed the utility of apparent diffusion coefficient (ADC) in combination with color Doppler flow imaging [ 8 ] and multi-phasic computer tomography (CT) [ 9 ] for classifying parotid gland lesions into benign and malignant tumors. However, the results were still not entirely satisfactory.…”

Section: Introductionsupporting

confidence: 66%

“…The diagnostic value of DWI in the characterization of parotid gland lesions is well recognized. Previous studies [ 8 , 23 ] pointed out that there were significant differences in ADC values among pleomorphic adenoma, Warthin’s tumor, and malignant tumor, while Warthin’s tumor had the lowest ADC values among these three. Paradoxically, Matsushima et al [ 24 ] found considerable limitations and no statistical difference in differentiation of benign from malignant parotid lesions by ADC values, possibly because Warthin’s tumor has a low ADC value due its mucus composition.…”

Section: Discussionmentioning

confidence: 99%

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Value of Diffusion-Weighted Imaging Combined with Susceptibility-Weighted Imaging in Differentiating Benign from Malignant Parotid Gland Lesions

et al. 2018

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BackgroundThe aim of this study was to investigate the diagnostic value of diffusion-weighted imaging (DWI) in combination with susceptibility-weighted imaging (SWI) for differentiating benign parotid gland lesions from malignant ones.Material/MethodsThis retrospective study was approved by the Ethics Committee of our hospital. A total of 36 patients (26 benign cases and 10 malignant cases) were confirmed by surgical pathology. The apparent diffusion coefficient (ADC), normalized ADC (ADCNormalized), intratumoral susceptibility signals (ITSS), and morphological characteristics were analyzed with SPSS 19.0 software.ResultsThe mean ADC values of parotid gland lesions was not different between malignant and benign lesions (P=0.07), while the differences between ADCNormalized (P=0.026) and ITSS grading (P=0.014) were statistically significant. Logistic regression analysis identified use of ADCNormalized and ITSS as the only independent predictor of malignant lesions (odds ratio 0.038; 95% confidence interval 0.001~0.988; P=0.011) and (odds ratio 4.867; 95% confidence interval 1.442~16.423; P=0.049), respectively. The optimum threshold of the ADCNormalized values was –0.45%, ITSS grade was 2, the corresponding areas under the receiver operating characteristic curve (AUC) were 0.750 and 0.787 respectively, and the combination of the 2 was 0.846.ConclusionsDWI integrated with SWI can significantly improve the diagnostic efficacy in distinguishing benign from malignant parotid lesions.

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Section: Introductionsupporting

confidence: 66%

Section: Discussionmentioning

confidence: 99%

Value of Diffusion-Weighted Imaging Combined with Susceptibility-Weighted Imaging in Differentiating Benign from Malignant Parotid Gland Lesions

et al. 2018

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“…Zheng et al [7] found that mean ADC value of 1.29 × 10 −3 mm 2 /s had 100% sensitivity and 91.7% specificity in differentiating pleomorphic adenoma from malignant parotid gland tumor. Several previous studies [7,[10][11][12][14][15][16][17][18] found that there was no significant difference between the mean ADC value of Warthin's tumor (mean ADC value ranged from 0.74 to 0.99 × 10 −3 mm 2 /s) and malignant parotid gland tumors (mean ADC value ranged from 0.795 to 1.21 × 10 −3 mm 2 /s). This is in agreement with our study.…”

Section: R E T R a C T E D A R T I C L Ementioning

confidence: 89%

“…Tao et al [12] found that mean ADC value of pleomorphic [14] stated that mean ADC values of pleomorphic adenoma and malignant parotid gland tumors was 1.35 × 10 −3 mm 2 /s and 0.94 × 10 −3 mm 2 /s respectively. Zang et al [15] found that mean ADC value of pleomorphic adenoma and malignant parotid gland tumors was 1.57 × 10 −3 mm 2 /s and 1.16 × 10 −3 mm 2 /s respectively. This is in agreement with our results where the mean ADC value for pleomorphic adenoma was 1.38 × 10 −3 mm 2 /s versus 1.08 × 10 −3 mm 2 /s for malignant parotid gland tumors (P = 0.046).…”

Section: R E T R a C T E D A R T I C L Ementioning

confidence: 99%

RETRACTED ARTICLE: The diagnostic value of combined dynamic contrast-enhanced MRI (DCE-MRI) and diffusion-weighted imaging (DWI) in characterization of parotid gland tumors

EL-Adalany

Mousa

EL-Metwally

2020

Egypt J Radiol Nucl Med

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Background MRI is considered to be the imaging modality of choice in preoperative diagnosis of parotid gland tumors and differentiating benign from malignant ones. Recently, functional MR imaging sequences including dynamic contrast-enhanced magnetic resonance imaging (DCE- MRI) and diffusion-weighted imaging (DWI) have significantly contributed to the diagnosis of head and neck masses. The purpose of this study was to evaluate the diagnostic value of combined DCE-MRI and DWI in characterization of parotid gland tumors. Results There was significant difference between benign and malignant parotid gland tumors as regard the type of time intensity curve (TIC) (P < 0.001). There was significant difference between pleomorphic adenoma (PMA) and malignant parotid gland tumors (MT) as regard mean ADC value (P = 0.046) and TTP (P = 0.002). There was no significant difference between Warthin’s tumor (WT) and malignant parotid gland tumors as regard the ADC value and TTP (P > 0.5); on the other hand, WT usually have high WR when compared with MT (P = 0.004). Combined use of DCE-MRI and DWI had 100% sensitivity, 90.5% specificity, and 93.3% accuracy in differentiating benign from malignant parotid gland tumors. Conclusion Combined use of DCE-MRI and DWI could result in high sensitivity, specificity, and diagnostic accuracy in characterization of parotid gland tumors.

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“…Therefore, differentiating between malignant and benign tumors based on B-mode and Doppler US is difficult and can lead to misdiagnosis. Zhang et al (2018) have showed that the diagnostic accuracy (96.1 vs 82.4%) of DWI-MRI was increased when ADC values were used in conjunction with US Doppler flow imaging features to differentiate parotid tumors compared to single usage of ADC values [24].…”

Section: Grayscale and Doppler Criteriamentioning

confidence: 99%

Ultrasonography techniques in the preoperative diagnosis of parotid gland tumors – an updated review of the literature

et al. 2020

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Preoperative diagnosis of parotid tumors plays a crucial role in selecting and planning the surgical treatment. Ultrasound (US) with its modern techniques can contribute to the differential diagnosis of parotid tumors. This paper aims to achieve a comprehensive review of the ultrasound techniques used in the differential diagnosis of parotid tumors, based on the latest literature data. Considering that most parotid gland tumors are located in the superficial lobe, US is frequently the first imaging technique used for the diagnosis of parotid tumors. Sonoelastography can provide additional data on the elasticity of parotid tumors, but there is an overlap between malignant and benign parotid tumors parameters. Contrast-enhanced ultrasound adds value to conventional ultrasound and allows a more complete characterization of parotid tumors. Many authors have reported promising results using contrast-enhanced ultrasound in the differential diagnosis of parotid tumors. Multiparametric ultrasound with a careful and systematic approach usually allows an accurate differential diagnosis of parotid tumors.

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Non-enhanced MRI in combination with color Doppler flow imaging for improving diagnostic accuracy of parotid gland lesions

Abstract: Combining CDFI with non-enhanced MRI can improve the diagnostic accuracy of MRI for classifying parotid gland lesions.

Cited by 14 publications

References 28 publications

Value of Diffusion-Weighted Imaging Combined with Susceptibility-Weighted Imaging in Differentiating Benign from Malignant Parotid Gland Lesions

Value of Diffusion-Weighted Imaging Combined with Susceptibility-Weighted Imaging in Differentiating Benign from Malignant Parotid Gland Lesions

RETRACTED ARTICLE: The diagnostic value of combined dynamic contrast-enhanced MRI (DCE-MRI) and diffusion-weighted imaging (DWI) in characterization of parotid gland tumors

Ultrasonography techniques in the preoperative diagnosis of parotid gland tumors – an updated review of the literature

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